GE28-9269-73
HiScreen™ MabSelect™
Cytiva 28-9269-73
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About This Item
Code UNSPSC :
13111000
Nomenclature NACRES :
NA.56
Produits recommandés
ligand
recombinant protein A (E. coli)
Fabricant/nom de marque
Cytiva 28-9269-73
Matrice
highly cross-linked agarose
cleaning
2-12
working range
3-10
Description générale
Determined at 10% breakthrough by frontal analysis at a mobile phase velocity of 500 cm/h in a column with a bed height of 20 cm.
HiScreen™ MabSelect™ is prepacked with MabSelect™ and is part of the process development platform available from Cytiva. The columns are an excellent choice for method optimization and parameter screening for capture of monoclonal antibodies (MAbs).
pH below 3 is sometimes required to elute strongly bound IgG species. However, protein ligands may hydrolyze at very low pH.
Application
The small column volume of 4.7 mL and bed height of 10 cm make HiScreen™ columns excellent tools for method optimization, parameter screening, robustness testing, and convenient scale-up. Process fluid velocities can be applied, since the 10 cm bed height gives enough residence time and the results can then serve as basis for linear process scale-up.
If necessary, two columns can easily be connected in series to give a bed height of 20 cm.
Media prepacked in HiScreen™ MabSelect™ columns are also available in other formats and as bulk packs, which makes it possible to use the same media for development work, pilot studies, and routine production.
If necessary, two columns can easily be connected in series to give a bed height of 20 cm.
Media prepacked in HiScreen™ MabSelect™ columns are also available in other formats and as bulk packs, which makes it possible to use the same media for development work, pilot studies, and routine production.
Caractéristiques et avantages
- MabSelect™ is a BioProcess medium for capture of MAbs from large sample volumes.
- Prepacked, ready-to-use columns for convenient process development.
- 10 cm bed height of HiScreen™ columns is designed to allow method optimization and parameter screening.
- Easily connected in series to achieve 20 cm bed height.
- Small bed volume gives fast results and minimal sample/buffer consumption.
- Reproducible results, scalable to BioProcess columns packed with the same chromatography media using the same linear fluid velocity.
Stockage et stabilité
Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
Remarque sur l'analyse
To view the Certificate of Analysis for this product, please visit www.cytiva.com.
Informations légales
HiScreen is a trademark of Cytiva
MabSelect is a trademark of Cytiva
Produit(s) apparenté(s)
Réf. du produit
Description
Tarif
Mention d'avertissement
Warning
Mentions de danger
Conseils de prudence
Code de la classe de stockage
3 - Flammable liquids
Certificats d'analyse (COA)
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