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Key Documents

E7525

Sigma-Aldrich

Anti-Ephrin-B2 antibody produced in goat

affinity isolated antibody

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About This Item

Numéro MDL:
Code UNSPSC :
51111800
Nomenclature NACRES :
NA.41

Source biologique

goat

Niveau de qualité

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Espèces réactives

mouse

Technique(s)

flow cytometry: 0.25 μg using 106 cells
immunocytochemistry: 5-15 μg/mL
western blot: 1 μg/mL

Numéro d'accès UniProt

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

mouse ... Efnb2(13642)

Catégories apparentées

Description générale

By immunoblotting and ELISA, the antibody shows ~50% cross-reactivity with recombinant human ephrin-B5 and 15% cross-reactivity with mouse ephrin-B1.

Immunogène

recombinant mouse ephrin-B2, expressed in NSO cells.

Actions biochimiques/physiologiques

Ephrin B2 binds to EPH receptor B, a protein-tyrosine kinase family that belongs to the ephrin receptor subfamily. EphB receptors and EphrinB ligands have a regulatory effect on endothelial cell function, angiogenesis, migration, cell growth and survival.

Forme physique

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline, pH 7.4 with 5% trehalose.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Consulter la Bibliothèque de documents

T Inada et al.
Blood, 89(8), 2757-2765 (1997-04-15)
HTK is a receptor tyrosine kinase of the Eph family. To characterize the involvement of HTK in hematopoiesis, we generated monoclonal antibodies against HTK and investigated its expression on human bone marrow cells. About 5% of the bone marrow cells
H U Wang et al.
Cell, 93(5), 741-753 (1998-06-18)
The vertebrate circulatory system is composed of arteries and veins. The functional and pathological differences between these vessels have been assumed to reflect physiological differences such as oxygenation and blood pressure. Here we show that ephrin-B2, an Eph family transmembrane
B D Bennett et al.
Proceedings of the National Academy of Sciences of the United States of America, 92(6), 1866-1870 (1995-03-14)
Htk is a receptor protein-tyrosine kinase that is related to the EPH subfamily of tyrosine kinases. The receptor has a wide tissue distribution including expression in several myeloid hematopoietic cell lines. Using an Htk-Fc fusion protein, a protein ligand for
T Vogt et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 4(3), 791-797 (1998-05-14)
The Lerks, ligands of eph-related receptor tyrosine kinases, are a rapidly expanding family of genes thought to play an important role in the development and oncogenesis of various tissues. However, very little experimental evidence supports this hypothesis. Using RNA fingerprinting
Ombretta Salvucci et al.
Advances in cancer research, 114, 21-57 (2012-05-17)
Eph receptor tyrosine kinases and their Ephrin ligands represent an important signaling system with widespread roles in cell physiology and disease. Receptors and ligands in this family are anchored to the cell surface; thus Eph/Ephrin interactions mainly occur at sites

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