Accéder au contenu
Merck
Toutes les photos(3)

Principaux documents

Voir toute la documentation

D3506

Sigma-Aldrich

Sodium diethyldithiocarbamate trihydrate

Synonyme(s) :

Cupral, Diethyldithiocarbamic acid sodium salt

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(3)

About This Item

Formule linéaire :
(C2H5)2NCSSNa · 3H2O
Numéro CAS:
20624-25-3
Poids moléculaire :
225.31
Beilstein:
3920507
Numéro CE :
205-710-6
Numéro MDL:
MFCD00150617
Code UNSPSC :
12352200
ID de substance PubChem :
57654092
Nomenclature NACRES :
NA.77

Densité de vapeur

5.9 (vs air)

Niveau de qualité

200

Essai

≥97% (perchloric acid titration)

Forme

powder or crystals

Pf

95-98.5 °C (lit.)

Solubilité

water: 1 g/10 mL, slightly hazy

Température de stockage

room temp

Chaîne SMILES 

[H]O[H].[H]O[H].[H]O[H].CCN(CC)C(=S)S[Na]

InChI

1S/C5H11NS2.Na.3H2O/c1-3-6(4-2)5(7)8;;;;/h3-4H2,1-2H3,(H,7,8);;3*1H2/q;+1;;;/p-1

Clé InChI

WWGXHTXOZKVJDN-UHFFFAOYSA-M

Vous recherchez des produits similaires ? Visite Guide de comparaison des produits

Application

Spin trap used in conjunction with Fe2+ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO2 has been reported. A copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.

Actions biochimiques/physiologiques

Inhibits induction of macrophage nitric oxide synthase.

Caractéristiques et avantages

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Dopamine, Norepinephrine and Epinephrine Synthesis page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Attention

May form insoluble oxidation products in storage. Sensitivity in colorimetric copper determination not usually affected.

Pictogrammes

CorrosionExclamation mark
GHS05,GHS07

Mention d'avertissement

Danger

Mentions de danger

H302,H315,H318

Classification des risques

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number
BCCD5391
BCBX0107
BCBS9779V
BCBQ4365V
BCBL3305V

Vous ne trouvez pas la bonne version ?

Si vous avez besoin d'une version particulière, vous pouvez rechercher un certificat spécifique par le numéro de lot.

Rechercher un(e) COA

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Les clients ont également consulté

Slide 1 of 2

1 of 2

Sodium dimethyldithiocarbamate solution ~40% in H2O

Sigma-Aldrich

71513

Sodium dimethyldithiocarbamate solution

Pentylmagnesium bromide solution 2.0 M in diethyl ether

Sigma-Aldrich

290998

Pentylmagnesium bromide solution

P E James et al.
Advances in experimental medicine and biology, 454, 181-187 (1999-01-16)
Although nitric oxide (NO) is a central mediator during endotoxin-induced sepsis, direct detection of tissue NO in vivo, has until recently been difficult, and techniques have relied on indirect measurement of bi-products in blood or invasive technology. We have utilized
Y Suzuki et al.
Free radical research, 28(3), 293-299 (1998-08-04)
To detect nitric oxide (NO) in the rat brain during lipopolysaccharide (LPS)-induced sepsis, electron paramagnetic resonance (EPR) was employed with the NO trapping technique, using an iron and N,N-diethyldithiocarbamate (DETC) complex. An X-band (about 9.5 GHz) EPR system detected a
Tianhui Liu et al.
British journal of pharmacology, 175(24), 4480-4495 (2018-09-29)
Diethyldithiocarbamate (DDC) is a major metabolite of disulfiram that is a potential drug for alcoholism treatment. In the present study, we attempted to explore the possible effect of DDC on non-alcoholic fatty liver disease (NAFLD) and related fibrosis in vivo.
Ji Youn Youn et al.
Redox biology, 46, 102099-102099 (2021-09-13)
The outbreak of COVID-19 has remained uncontained with urgent need for robust therapeutics. We have previously reported sex difference of COVID-19 for the first time indicating male predisposition. Males are more susceptible than females, and more often to develop into
Jonathan H Pérez et al.
The Journal of experimental biology, 223(Pt 1) (2019-12-05)
The hypothalamic-pituitary-adrenal (HPA) axis is under complex regulatory control at multiple levels. Enzymatic regulation plays an important role in both circulating levels of glucocorticoids and target tissue exposure. Three key enzyme pathways are responsible for the immediate control of glucocorticoids.
Afficher tous les articles scientifiques apparentés

Contenu apparenté

Discover Bioactive Small Molecules for ADME/Tox

Discover Bioactive Small Molecules for ADME/Tox

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique