OX-24

Reactivity: Anti-Factor H, human, 00010403

• Code UNSPSC : 41106514

Propriétés

• Source biologique: Mouse x Mouse Hybridoma
• ImmunoDon: BALB/c mouse spleen
• Myélome: NS0
• Réactivité: Anti-Factor H, human
• Technique(s): cell culture | mammalian: suitable
• Isotype: IgG1
• Conditions d'expédition: dry ice
• Température de stockage: −196°C

Description

Origine de la lignée cellulaire

Mouse x Mouse hybridoma

Description de la lignée cellulaire

The hybridoma line OX-24 was developed by immunizing BALB/c mice with Factor H followed by fusion of spleen cells with NS0 mouse myeloma cells. The antibody was shown to detect the human complement control protein, Factor H. OX-24, which is also known as MRC-OX24 was reported to increase cofactor activity of Factor H in Factor I-mediated cleavage of soluble C3b. The antibody inhibited the binding of radioactive-labelled Factor H to surface-bound C3b. OX-23 (Sigma Catalogue number. 00010402) was shown to decrease this inhibition.

Immunogène

Human Factor H

Milieu de culture

RPMI 1640 (R0883) + 2mM Glutamine (G7513) + 10% FBS / FCS (F2442)

Procédure de repiquage

Maintain cultures between 3-9 x 100,000 cells/ml; 5% CO₂; 37°C.

Autres remarques

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Clause de non-responsabilité

This cell line has special release conditions: Commercial organisations are required to complete the ′Cell Line Release Authorisation for Research Use in Commercial Organisations′ release conditions form.