A7641

Albumine from chicken egg white

lyophilized powder

• Synonyme(s) : Albumine from hen egg white, Ovalbumine
• Numéro CAS: 9006-59-1
• Numéro CE : 232-692-7
• Numéro MDL: MFCD00130424
• Code UNSPSC : 12352202
• eCl@ss : 42010201
• Nomenclature NACRES : NA.25

Propriétés

• Source biologique: chicken egg white
• Type: Grade VII
• Pureté: ≥95% (agarose gel electrophoresis)
• Forme: lyophilized powder
• Poids mol.: 44287 Da by calculation
• Produit purifié par: chromatography
• Technique(s): bioconjugation: suitable
• Numéro d'accès UniProt: P01012
• Température de stockage: 2-8°C
• Informations sur le gène: chicken ... OVAL(396058)

Description

Description générale

Chicken egg albumin is the major protein constituent of egg whites. Chicken egg albumin is a phosphorylated-glycoprotein. From the amino acid sequence, the peptide portion of the molecule consists of 385 residues and has a molecular weight of 42.7 kDa.

Ovalbumin, an egg white protein is produced in the oviduct of hen. It has 3 sites of post synthetic modification and an N-terminal acetyl group. This product is free of S-ovalbumin, a heat stable form of egg albumin formed when eggs are stored.

Application

Albumin from chicken egg white has been used:

• as a component in reaction buffer for in vitro enzymatic assay
• to simulate dangerous protein toxins
• as a component in marker solution

The product is useful as a marker (∼45 kDa) for protein electrophoresis. It has been used to produce an animal model of asthma.
Ovalbumin was used as medium for cell incubation in EliCell assay for the detection of released cytokines from eosinophil.
It was also used in a study testing intestinal macromolecule absorption in fetal pig after infusion of colostrum in utero.

Protéine phosphorylée qui sert de marqueur (env. 45 kDa) dans l′électrophorèse de protéines. Elle a été employée pour créer un modèle de l′asthme chez l′animal.

Actions biochimiques/physiologiques

Differential scanning calorimetry indicates that chicken egg albumin denatures at 84 °C. Ovalbumin can be used as a carrier protein to conjugate to synthetic peptides for use as an immunogen.

Ovalbumin is preferred as a nutrient supplement. It can serve as a drug carrier. It possess tumor necrosis releasing factors, that can play a great role in tumor suppression.

Informations sur la sécurité

• Pictogrammes: GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H334
• Conseils de prudence: P261 - P284 - P304 + P340 + P312 - P501
• Classification des risques: Resp. Sens. 1A
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)