A6428

Aflatoxin M₁

from Aspergillus flavus

• Formule empirique (notation de Hill): C₁₇H₁₂O₇
• Numéro CAS: 6795-23-9
• Poids moléculaire : 328.27
• Numéro CE : 229-865-4
• Numéro MDL: MFCD00871812
• Code UNSPSC : 12352200
• ID de substance PubChem : 24891088
• Nomenclature NACRES : NA.77

Propriétés

• Source biologique: Aspergillus flavus
• Niveau de qualité: 200
• Forme: film
• Température de stockage: 2-8°C
• Chaîne SMILES: [H][C@]12OC=C[C@@]1(O)c3c(O2)cc(OC)c4C5=C(C(=O)CC5)C(=O)Oc34
• InChI: 1S/C17H12O7/c1-21-9-6-10-13(17(20)4-5-22-16(17)23-10)14-12(9)7-2-3-8(18)11(7)15(19)24-14/h4-6,16,20H,2-3H2,1H3/t16-,17-/m1/s1
• Clé InChI: MJBWDEQAUQTVKK-IAGOWNOFSA-N

Description

Description générale

Aflatoxins are metabolites of fungus, that are mainly seen in feeds and foods. Aflatoxin M₁ is a hydroxylated metabolite of aflatoxin B₁. It is liberated in milk, urine and produced in liver after receiving aflatoxin B₁.

Application

Aflatoxin M1 has been used as a standard to investigate the incidence and occurrence of aflatoxin M₁ (AFM₁) in Brazilian milk and infant formula. It has also been used as standard to investigate the incidence and occurrence of aflatoxin M1 (AFM₁) in dairy products produced in Brazil.

Aflatoxin M1 is both a hepatotoxic and hepatocarcinogenic mycotoxin that has been shown to cause immunosuppression in animals.

Actions biochimiques/physiologiques

Aflatoxin M1 possesses hepatocarcinogenic properties.

Avertissement

Possibly carcinogenic.

Notes préparatoires

Aspergillus flavus metabolite.

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H300 + H310 + H330,H340,H350
• Conseils de prudence: P202 - P260 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Classification des risques: Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Carc. 1B - Muta. 1B
• Code de la classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable