93659

L-Tryptophane

≥99.5% (NT), BioUltra

• Synonyme(s) : Acide L-α-amino-3-indolepropionique, Acide (S)-2-amino-3-(3-indolyl)propionique
• Formule empirique (notation de Hill): C₁₁H₁₂N₂O₂
• Numéro CAS: 73-22-3
• Poids moléculaire : 204.23
• Numéro Beilstein : 86197
• Numéro CE : 200-795-6
• Numéro MDL: MFCD00064340
• Code UNSPSC : 12352209
• eCl@ss : 32160406
• ID de substance PubChem : 57653570
• Nomenclature NACRES : NA.26

Propriétés

• product name: L-Tryptophane, BioUltra, ≥99.5% (NT)
• Gamme de produits: BioUltra
• Pureté: ≥99.5% (NT)
• Forme: powder or crystals
• Activité optique: [α]20/D −31.5±1°, c = 1% in H₂O
• Impuretés: insoluble matter, passes filter test
• Résidus de calcination: ≤0.1%
• Perte: ≤0.1% loss on drying, 20 °C (HV)
• Couleur: white
• Pf: 280-285 °C (dec.) (lit.)
• Solubilité: 0.5 M HCl: 0.1 g/mL at 20 °C, clear, colorless to faintly yellow
• Traces d'anions: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• Traces de cations: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• Absorption: cut-off at 326 nm in 0.5 M HCl at 0.5 M
• Application(s): cell analysis
• Chaîne SMILES: N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
• InChI: 1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1
• Clé InChI: QIVBCDIJIAJPQS-VIFPVBQESA-N

Description

Application

L-Tryptophan has been used as a nutritional supplement to study its effect on the circadian clock of primary cell lines. It has also been used as a test amino acid aerosol to study the variation in the fluorescence intensity of thermally-exposed bacterial bioaerosols.

Actions biochimiques/physiologiques

Tryptophan (Trp) is one of the functional amino acids that are associated with growth, reproduction, maintenance and immunity. Increased Trp availability is necessary for the regulation of mood, cognition and behaviour. It is hypothesised that L-Trp might be useful in inducing sleep in healthy adults against the normal circadian rhythm. Trp uptake by the brain depends on the plasma ratio of Trp to all of the other LNAAs (large neutral amino acids). Higher the Trp:LNAAs ratio, greater is the Trp uptake.

Autres remarques

Acide aminé précurseur de la sérotonine et de la mélatonine

In tryptophan-substituted Sephadex^® and Sepharose^™ for the improved chromatographic separation of cellulases; As spacer in isotachophoresis of serum proteins; Growth requirement of various microorganisms.

Informations légales

Sephadex is a registered trademark of Cytiva

Sepharose is a trademark of Cytiva

Informations sur la sécurité

• Code de la classe de stockage: 13 - Non Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)