72987

2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose

≥97% (HPLC)

• Synonyme(s) : 2-NBDG, 2-[N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-2-deoxy-D-glucose
• Formule empirique (notation de Hill): C₁₂H₁₄N₄O₈
• Numéro CAS: 186689-07-6
• Poids moléculaire : 342.26
• Numéro Beilstein : 7603370
• Numéro MDL: MFCD23135882
• Code UNSPSC : 12352108
• ID de substance PubChem : 329764517
• Nomenclature NACRES : NA.32

Propriétés

• Source biologique: synthetic
• Niveau de qualité: 100
• Pureté: ≥97% (HPLC)
• Forme: powder
• Fluorescence: λ_ex 494 nm; λ_em 551 nm in DMSO
• Application(s): cell analysis
• Température de stockage: −20°C
• Chaîne SMILES: OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](Nc1ccc([N+]([O-])=O)c2nonc12)C=O
• InChI: 1S/C12H14N4O8/c17-3-6(11(20)12(21)8(19)4-18)13-5-1-2-7(16(22)23)10-9(5)14-24-15-10/h1-3,6,8,11-13,18-21H,4H2/t6-,8+,11+,12+/m0/s1
• Clé InChI: QUTFFEUUGHUPQC-ILWYWAAHSA-N

Description

Description générale

2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl) amino]-D-glucose, also known as 2-NBDG, is a fluorescent D-glucose analog. The consequent fluorescent activity is detected by flow cytometry. 2-NBDG is incubated directly with the test sample for uptake, followed by measurement.

Application

2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl) amino]-D-glucose is used as a fluorescent indicator for direct glucose uptake measurement. 2-NBDG is used as a fluorescent deoxyglucose analog to study the tumor cells. For in vivo imaging of epileptic activity experiments, 2-NBDG is used as a fluorescent deoxyglucose analog.

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable