422R-1

PHOX2B (EP312) Rabbit Monoclonal Primary Antibody

• Synonyme(s) : Paired-like Homeobox 2B
• Code UNSPSC : 12352203

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100; 500
• Conjugué: unconjugated
• Forme d'anticorps: culture supernatant
• Type de produit anticorps: primary antibodies
• Clone: EP312, monoclonal
• Description: For In Vitro Diagnostic Use in Select Regions
• Forme: buffered aqueous solution
• Espèces réactives: human
• Conditionnement: vial of 0.1 mL concentrate (422R-14); vial of 0.1 mL concentrate Research Use Only (422R-14-RUO); vial of 0.5 mL concentrate (422R-15); vial of 1.0 mL concentrate (422R-16); vial of 1.0 mL concentrate Research Use Only (422R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (422R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (422R-17); vial of 7.0 mL pre-dilute ready-to-use (422R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (422R-18-RUO)
• Fabricant/nom de marque: Cell Marque^™
• Technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• Isotype: IgG
• Contrôle: neuroblastoma
• Conditions d'expédition: wet ice
• Température de stockage: 2-8°C
• Visualisation: nuclear
• Informations sur le gène: human ... PHOX2B(8929)

Description

Description générale

Paired-like homeobox 2B (PHOX2B) is a transcription factor located on chromosome 4p13 which is crucial to the formation of autonomic ganglia in the autonomic nervous system (ANS). PHOX2B gene is strictly expressed in neural crest derivatives committed to the noradrenergic phenotype. The PHOX2B gene encodes a paired-like homeo-domain transcription factor with an extra-axial expression pattern restricted to the ANS. Neuroblasts of peripheral neuroblastic tumors are derived from the sympathoadrenal lineage, a division of the ANS. PHOX2B has been observed in peripheral neuroblastic tumors, neuroblastomas, paragangliomas, ganglioneuroblastomas, ganglioneuromas and pheochromocytomas. PHOX2B has been reported to be negative in other small round blue cell tumors.

Qualité

IVD

IVD

IVD

RUO

Liaison

PHOX2B Positive Control Slides, Product No. 422S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forme physique

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Notes préparatoires

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Autres remarques

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informations légales

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable