Accéder au contenu
Merck
Toutes les photos(1)

Documents

363R-3

Sigma-Aldrich

PAX-8 (SP348) Rabbit Monoclonal Antibody

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme


About This Item

Code UNSPSC :
12352203

Source biologique

rabbit blood

Niveau de qualité

Conjugué

unconjugated

Forme d'anticorps

IgG fraction of tissue culture supernatant

Type de produit anticorps

primary antibodies

Clone

SP348

Description

For In Vitro Diagnostic Use in Select Regions

Forme

buffered aqueous solution

Espèces réactives

human

Conditionnement

vial of 0.1 mL (concentrate (363R-34-RUO) Research Use Only)
vial of 0.1 mL
(concentrate (363R-34))

vial of 0.5 mL (concentrate (363R-35))
vial of 1.0 mL (concentrate (363R-36))
vial of 1.0 mL (concentrate (363R-36-RUO) Research Use Only)
vial of 1.0 mL (pre-dilute (363R-37-RUO) Research Use Only)
vial of 1.0 mL (pre-dilute ready-to-use (363R-37))
vial of 25.0 mL (pre-dilute ready-to-use (363R-30))
vial of 25.0 mL (pre-dilute ready-to-use (363R-30-RUO))
vial of 7.0 mL (pre-dilute ready-to-use (363R-38))
vial of 7.0 mL (pre-dilute ready-to-use (363R-38-RUO) Research Use Only)

Fabricant/nom de marque

Cell Marque

Technique(s)

immunocytochemistry: suitable (formalin-fixed, paraffin-embedded sections 1:10-1:20 (concentrated))

Isotype

IgG

Contrôle

ovarian carcinoma, papillary carcinoma of thyroid, renal cell carcinoma, (Fallopian Tube)

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Visualisation

nuclear

Description générale

PAX-8 is a transcription factor expressed during embryonic development of Müllerian organs, kidney, and thyroid, with continued expression in neoplastic transformation of some epithelial cell types of these mature tissues.1 It can be useful for marking several types of carcinoma including, but not limited to, ovarian serous carcinoma, clear cell renal cell carcinoma and papillary thyroid carcinoma. Certain anti-PAX-8 antibodies may react with lymphocytes and their neoplasms, which has been attributed to cross-reactivity with PAX-5 due to sequence homology between PAX-8 and PAX-5, but clone SP348 does not exhibit reactivity in these cell types.

Qualité

United States - IVD
Canada - RUO
European Union - IVD
Japan - RUO

Forme physique

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Notes préparatoires

Download the IFU specific to your product lot and format
Note: This requires a keycode which can be found on your packaging or product label.

Autres remarques

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informations légales

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Not finding the right product?  

Try our Outil de sélection de produits.

Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Guo-Xia Tong et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 22(9), 1218-1227 (2009-06-16)
Cell-lineage-specific transcription factors are a group of regulatory proteins expressed in embryonic, differentiated, or neoplastic cells of the same lineage and represent a valuable repertoire of tissue-specific markers for the diagnosis of human tumors. Together with PAX2, PAX8 is a

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique