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Key Documents

147M-9

Sigma-Aldrich

CD45RO (UCHL-1) Mouse Monoclonal Antibody

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

100
500

Conjugué

unconjugated

Forme d'anticorps

culture supernatant

Type de produit anticorps

primary antibodies

Clone

UCHL-1, monoclonal

Description

For In Vitro Diagnostic Use in Select Regions (See Chart)

Forme

buffered aqueous solution

Espèces réactives

human

Conditionnement

vial of 0.1 mL concentrate (147M-94)
vial of 0.5 mL concentrate (147M-95)
bottle of 1.0 mL predilute (147M-97)
vial of 1.0 mL concentrate (147M-96)
bottle of 7.0 mL predilute (147M-98)

Fabricant/nom de marque

Cell Marque

Technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

Isotype

IgG2aκ

Contrôle

tonsil

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Visualisation

membranous

Informations sur le gène

human ... PTPRC(5788)

Description générale

Anti-CD45RO (T-Cell, Pan) antibody reacts with thymocytes and activated T-cells, but only on a subpopulation of resting T-cells. This antibody shows no reactivity with B-cells making it a good marker for T-cell tumors. In addition, granulocytes and monocytes are also labeled with this antibody. T-Cell, Pan has been designated as CD45RO at The International Leukocyte Typing Workshop.

Qualité


IVD

IVD

IVD

RUO

Liaison

CD45RO Positive Control Slides, Product No. 147S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forme physique

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Notes préparatoires

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Autres remarques

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informations légales

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Consulter la Bibliothèque de documents

A E Koch et al.
Journal of clinical immunology, 10(4), 192-199 (1990-07-01)
We have characterized the lymphocytes in the synovium of patients with rheumatoid arthritis (RA) by immunohistochemistry using monoclonal antibodies directed against B lymphocytes, T lymphocytes, and antibodies directed against CD45RA and CD45RO, which define T-cell subsets. Both CD45RA+ and CD45RO+
J A Tworek et al.
American journal of clinical pathology, 110(5), 582-589 (1998-11-05)
Small lymphocytic lymphoma (SLL), mantle cell lymphoma (MCL), and SLL plasmacytoid (SLLP) are malignant neoplasms of small B cells that may have overlapping cytologic features. Entities such as SLL with irregular nuclear contours may pose additional diagnostic difficulties. We investigated
B Falini et al.
Human pathology, 21(6), 624-629 (1990-06-01)
Monoclonal antibodies (mAbs) directed against the leucocyte common (CD45) antigen have been proposed as a useful tool for the differential diagnosis between malignant lymphomas (CD45+) and poorly differentiated nonhemopoietic tumors (CD45-). Thanks to the availability of mAbs directed against fixative-resistant
P A Hall et al.
Journal of clinical pathology, 40(2), 151-156 (1987-02-01)
The use of the murine monoclonal antibody MB2 for identifying B lymphocytes in routinely processed tissue was evaluated and contrasted with the use of the monoclonal antibody UCHL1 for identifying T cells. One hundred and sixty eight surgical biopsy specimens
J H Ritter et al.
Journal of cutaneous pathology, 21(6), 481-493 (1994-12-01)
In the skin, separation of selected lymphomas from lymphoid hyperplasia can be challenging. The authors examined 45 cutaneous lymphomas, excluding mycosis fungoides (26 small lymphocytic or mixed tumors; 19 large cell lymphomas), 10 "atypical" lesions, and 40 lesions of presumed

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