143R-1

CD43 (SP55) Rabbit Monoclonal Antibody

• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 500
• Conjugué: unconjugated
• Forme d'anticorps: culture supernatant
• Type de produit anticorps: primary antibodies
• Clone: SP55, monoclonal
• Description: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Forme: buffered aqueous solution
• Espèces réactives: human
• Conditionnement: vial of 0.1 mL concentrate (143R-14); vial of 0.5 mL concentrate (143R-15); bottle of 1.0 mL predilute (143R-17); vial of 1.0 mL concentrate (143R-16); bottle of 7.0 mL predilute (143R-18)
• Technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
• Isotype: IgG1
• Contrôle: tonsil
• Conditions d'expédition: wet ice
• Température de stockage: 2-8°C
• Visualisation: membranous
• Informations sur le gène: human ... SPN(6693)

Description

Description générale

CD43, also called leukosialin, is expressed on the surface of all leukocytes except for some resting B-cells. It appears to function as an anti-adhesion molecule, mediating repulsion amongst leukocytes. CD43 expression in lymphomas is highly correlated with CD5; thus most T-cell malignancies and a group of small lymphocyte B-cell malignancies [CLL/ SLL, mantle cell lymphoma (MCL), prolymphocytic leukemia] are often positive, while follicular lymphoma (FL) is usually negative. Anti-CD43 is less useful as a lineage marker, but is a sensitive indicator of aberrant B-cell populations. From 70 to 90% of T-cell lymphomas are labeled with this antibody. Plasmacytoma/myeloma and mast cell disease are also labeled with this antibody. No reactivity has been observed with reactive B-cells.

Qualité

IVD

IVD

IVD

RUO

Liaison

CD43 Positive Control Slides, Product No. 143S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forme physique

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Notes préparatoires

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Autres remarques

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Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable