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Key Documents

107689

Sigma-Aldrich

Hexadimethrine bromide

≥95%

Synonyme(s) :

1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide, Polybrene

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About This Item

Numéro CAS:
Numéro MDL:
Code UNSPSC :
41106502
Nomenclature NACRES :
NA.26

Pureté

≥95%

Température de stockage

2-8°C

InChI

1S/C10H24N2.C3H6Br2/c1-11(2)9-7-5-6-8-10-12(3)4;4-2-1-3-5/h5-10H2,1-4H3;1-3H2

Clé InChI

KZKAYEGOIJEWQB-UHFFFAOYSA-N

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Application


  • Adaptive and Ultrahigh-Affinity Recognition in Water by Sulfated Conjugated Corral[5]arene.: Research on Hexadimethrine bromide′s interaction with sulfated corral[5]arene under aqueous conditions, exploring its high-affinity binding properties which could be crucial for developing new biochemical sensors (Wang et al., 2024).

Pictogrammes

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Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Consulter la Bibliothèque de documents

G Montalescot et al.
Circulation, 82(5), 1754-1764 (1990-11-01)
Protamine reversal of heparin anticoagulation in patients is occasionally associated with life-threatening acute pulmonary hypertension. In a sheep model, we evaluated the effect on this adverse cardiopulmonary reaction of modifying the type of heparin (low molecular weight heparin compared with
Noam Auslander et al.
Molecular systems biology, 13(12), 956-956 (2017-12-03)
Metabolic alterations play an important role in cancer and yet, few metabolic cancer driver genes are known. Here we perform a combined genomic and metabolic modeling analysis searching for metabolic drivers of colorectal cancer. Our analysis predicts FUT9, which catalyzes
Abdulrahman Jama et al.
The Journal of physiology, 597(3), 889-901 (2018-12-05)
Lipin1 is critical for skeletal muscle development. Lipin1 regulates MyoD and myocyte-specific enhancer factor 2C (MEF2c) expression via the protein kinase C (PKC)/histone deacetylase 5-mediated pathway. Inhibition of PKCμ activity suppresses myoblast differentiation by inhibiting MyoD and MEF2c expression. Our
Jian Zhang et al.
Cell death & disease, 10(8), 599-599 (2019-08-10)
Advances in the molecular characteristics of cancers have facilitated the classification system from morphology to molecular characteristic-based subtypes. Cancer profiling has expanded in its focus from protein-coding genes to noncoding RNAs, with advances in the depth and quality of transcriptome
Kelly Foley et al.
Cell adhesion & migration, 11(5-6), 514-523 (2017-02-06)
Pancreatic adenocarcinoma (PDA) is characterized by a dense desmoplastic reaction that comprises 60-90% of the tumor, while only 10-40% of the tumor is composed of malignant epithelial cells. This desmoplastic reaction is composed of stromal fibroblast cells, extracellular matrix proteins

Articles

Polybrene® is a well-known anti-heparin agent. Also known as 1,5-dimethyl-1,5-diazaundecamethylene polymethobromide and hexadimethrine bromide, this positively charged polymer produces non-specific red blood cell agglutination by neutralizing the red blood cell net negative charge.

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