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Key Documents

01148

Sigma-Aldrich

Sodium fluoride

puriss., meets analytical specification of Ph. Eur., BP, USP, 98.5-100.5% (calc. to the dried substance)

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About This Item

Formule linéaire :
NaF
Numéro CAS:
Poids moléculaire :
41.99
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352302
eCl@ss :
38050104
ID de substance PubChem :
Nomenclature NACRES :
NA.21

Pression de vapeur

1.4 mmHg ( 0 °C)

Qualité

puriss.
meets analytical specification of Ph. Eur., BP, USP

Pureté

98.5-100.5% (calc. to the dried substance)

Forme

powder

Impuretés

acidity or alkalinity, complies
organic volatile impurities, complies (GC)
residual solvents, complies
≤0.002% heavy metals (as Pb)
≤0.1% free alkali (as NaOH)
≤0.2% free acid (as HF)
≤0.2% sodium hexafluorosilicate (Na2SiF6)

Perte

≤0.5% loss on drying, 150 °C

Pf

993 °C (lit.)

Traces d'anions

chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤200 mg/kg

Traces de cations

Fe: ≤50 mg/kg

Adéquation

complies for appearance of solution

Chaîne SMILES 

[F-].[Na+]

InChI

1S/FH.Na/h1H;/q;+1/p-1

Clé InChI

PUZPDOWCWNUUKD-UHFFFAOYSA-M

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Description générale

Sodium fluoride (NaF) is a metallic halide. It has been reported as dental caries preventive agent. It is the most widely employed preservative for glucose in blood. It has been reported to stabilize hepatic microsomal glucose-6-P phosphohydrolase enzyme.

Application

Sodium fluoride may be employed as fluorination agent in the synthesis of aromatic and aliphatic fluorides, via metathesis. It may be used to prepare the lysis buffer.

Pictogrammes

Skull and crossbones

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

Risques supp

Code de la classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Effectiveness of sodium fluoride as a preservative of glucose in blood.
Chan AY, et al.
Clinical Chemistry, 35(2), 315-317 (1989)
A J Lange et al.
The Journal of biological chemistry, 261(1), 101-107 (1986-01-05)
Stabilization and inhibition of hepatic microsomal glucose-6-P phosphohydrolase (EC 3.1.3.9) by F- requires the presence of Al3+ ions. At millimolar concentrations, reagent grade NaF inhibited glucose-6-P hydrolysis and protected the enzyme against inactivation induced by heat in the presence of
Synthesis of fluorides by metathesis with sodium fluoride.
Tullock CW and Coffman DD.
The Journal of Organic Chemistry, 25(11), 2016-2019 (1960)
J G Drachman et al.
The Journal of biological chemistry, 270(10), 4979-4982 (1995-03-10)
c-Mpl is a member of the cytokine receptor superfamily, expressed primarily on hematopoietic cells. Recently, the c-Mpl ligand was cloned and found to have thrombopoietic activity. In this paper we report that ligand binding induced tyrosine phosphorylation in BaF3 cells
Hye-Jin Lee et al.
The Kaohsiung journal of medical sciences, 31(6), 303-308 (2015-06-05)
Dental caries preventive agents, such as sodium fluoride (NaF) and bamboo salt (BS), are known to cause cellular growth that is characterized by morphological and gene expression changes. This study was designed to investigate the dual effect of NaF and

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