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Y0001355

Prednisolone for system suitability

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

1,4-pregnadiène-11β,17α,21-triol-3,20-dione, 11β,17α,21-trihydroxy-1,4-pregnadiène-3,20-dione

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About This Item

Formule empirique (notation de Hill):
C21H28O5
Numéro CAS:
50-24-8
Poids moléculaire :
360.44
Numéro Beilstein :
1354103
Numéro MDL:
MFCD00003649
Code UNSPSC :
41116107
ID de substance PubChem :
329831377
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

prednisolone

Fabricant/nom de marque

EDQM

Pf

240 °C (dec.) (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(CO)=O)=C1

InChI

1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

Clé InChI

OIGNJSKKLXVSLS-VWUMJDOOSA-N

Informations sur le gène

human ... NR3C1(2908)

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Prednisolone for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

PHR1043

Prednisolone, Pharmaceutical Secondary Standard; Certified Reference Material

P2700000

Prednisolone, European Pharmacopoeia (EP) Reference Standard

P2800000

Prednisolone 21-acetate, European Pharmacopoeia (EP) Reference Standard

P2810000

Prednisolone sodium phosphate, European Pharmacopoeia (EP) Reference Standard

Y0001359

Prednisolone for peak identification, European Pharmacopoeia (EP) Reference Standard

P2805000

Prednisolone pivalate, European Pharmacopoeia (EP) Reference Standard

Y0000582

Prednisolone 21-acetate, European Pharmacopoeia (EP) Reference Standard

1557000

Prednisolone sodium phosphate, United States Pharmacopeia (USP) Reference Standard

1555005

Prednisolone, United States Pharmacopeia (USP) Reference Standard

1556008

Prednisolone 21-acetate, United States Pharmacopeia (USP) Reference Standard

1556507

Prednisolone hemisuccinate, United States Pharmacopeia (USP) Reference Standard

1558003

Prednisolone tebutate, United States Pharmacopeia (USP) Reference Standard

BP464

Prednisolone, British Pharmacopoeia (BP) Assay Standard

BP292

Prednisolone sodium phosphate, British Pharmacopoeia (BP) Assay Standard

PHR1630

Prednisolone 21-acetate, Pharmaceutical Secondary Standard; Certified Reference Material

BP1140

Prednisolone 21-acetate, British Pharmacopoeia (BP) Reference Standard

PHR2556

Prednisolone Impurity H, Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard

PHR2557

Prednisolone Impurity I, certified reference material, pharmaceutical secondary standard

PHR2328

Prednisolone Impurity G, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2816

Prednisolone Sodium Phosphate, certified reference material, pharmaceutical secondary standard

Pictogrammes

Health hazard
GHS08

Mention d'avertissement

Danger

Mentions de danger

H360FD

Classification des risques

Repr. 1B

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 2

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Certificats d'analyse (COA)

Lot/Batch Number

Désolés, nous n'avons pas de COA pour ce produit disponible en ligne pour le moment.

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Arzu Didem Yalcin et al.
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J A P Spijkers-Hagelstein et al.
Leukemia, 28(4), 761-769 (2013-08-21)
Successful treatment results for MLL-rearranged Acute Lymphoblastic Leukemia (ALL) in infants remain difficult to achieve. Significantly contributing to therapy failure is poor response to glucocorticoids (GCs), like prednisone. Thus, overcoming resistance to these drugs may be a crucial step towards
Axel Heidenreich et al.
European journal of cancer (Oxford, England : 1990), 50(6), 1090-1099 (2014-02-04)
Cabazitaxel/prednisone has been shown to prolong survival versus mitoxantrone/prednisone in patients with metastatic castration-resistant prostate cancer (mCRPC) that has progressed during or after docetaxel. Subsequently, compassionate-use programmes (CUPs) and expanded-access programmes (EAPs) were established worldwide, allowing access to cabazitaxel before
Eng Cern Gan et al.
International forum of allergy & rhinology, 4(11), 877-884 (2014-08-20)
The endoscopically magnified operative field in functional endoscopic sinus surgery (FESS) makes even a small amount of bleeding a potentially significant hindrance. It is thought that irrigation with hot saline during surgery may improve surgical field of view by producing
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