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PHR2006

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Allopurinol Related Compound B

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

3-(Formylamino)-1H-pyrazole-4-carboxamide, 5-(Formylamino)-1H-pyrazole-4-carboxamide

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About This Item

Formule empirique (notation de Hill):
C5H6N4O2
Numéro CAS:
Poids moléculaire :
154.13
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

certified reference material
pharmaceutical secondary standard

Niveau de qualité

Agence

traceable to BP 832
traceable to Ph. Eur. A0350020
traceable to USP 1013013

Famille d'API

allopurinol

CofA (certificat d'analyse)

current certificate can be downloaded

Conditionnement

pkg of 50 mg

Application(s)

pharmaceutical

Format

neat

Température de stockage

2-8°C

InChI

1S/C5H6N4O2/c6-4(11)3-1-8-9-5(3)7-2-10/h1-2H,(H2,6,11)(H2,7,8,9,10)

Clé InChI

MKVXRGIJTKYXPR-UHFFFAOYSA-N

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Description générale

Allopurinol Related Compound B is an impurity of allopurinol. Allopurinol is a purine analog and a structural isomer of the naturally available purine in the body, hypoxanthine. It is also a powerful xanthine oxidase inhibitor. It is widely utilized against purine and pyrimidine metabolic disorders that give rise to an excess of uric acid in humans.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Allopurinol Related Compound B may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Autres remarques

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAB7872 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

High-performance liquid chromatography with polarographic and voltammetric anodic detection: simultaneous determination of allopurinol, oxipurinol and uric acid in body fluids
Palmisano F, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 306(1), 205-214 (1984)
Allopurinol
USP42-NF37: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 34(1), 132-132 (2018)
Development of a stability indicating RP-RRLC method for determination of allopurinol and its degradation products in solid oral dosage
Singh S and Gadhawala Z
International Journal of PharmTech Research, 5(1), 44-53 (2013)

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