PHR1530

Acetaminophen Related Compound D

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonyme(s) : Acetanilide, N-Phenylacetamide
• Formule linéaire : CH₃CONHC₆H₅
• Numéro CAS: 103-84-4
• Poids moléculaire : 135.16
• Numéro Beilstein : 606468
• Numéro CE : 203-150-7
• Numéro MDL: MFCD00008674
• Code UNSPSC : 41116107
• ID de substance PubChem : 329823442
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material; pharmaceutical secondary standard
• Niveau de qualité: 300
• Agence: traceable to USP 1003042
• Densité de vapeur: 4.65 (vs air)
• Pression de vapeur: 1 mmHg ( 114 °C)
• Description: API family: acetaminophen
• Famille d'API: acetaminophen, paracetamol
• CofA (certificat d'analyse): current certificate can be downloaded
• Température d'inflammation spontanée: 1004 °F
• Conditionnement: pkg of 200 mg
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Point d'ébullition: 304 °C (lit.)
• Pf: 113-115 °C (lit.)
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Température de stockage: 2-30°C
• Chaîne SMILES: CC(=O)Nc1ccccc1
• InChI: 1S/C8H9NO/c1-7(10)9-8-5-3-2-4-6-8/h2-6H,1H3,(H,9,10)
• Clé InChI: FZERHIULMFGESH-UHFFFAOYSA-N

Description

Description générale

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

It is an impurity of the widely used antipyretic and analgesic drug acetaminophen, also known as paracetamol.

Application

This pharmaceutical secondary standard can also be used as follows:

• Detection and quantification of paracetamol, phenylephrine hydrochloride, and paracetamol impurities in pharmaceutical formulations using four chemometric-based spectrophotometric methods
• Simultaneous determination of paracetamol and phenylephrine hydrochloride in the presence of paracetamol-related impurities using capillary zone electrophoresis (CZE) in their combined tablet forms

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAA3648 in the slot below. This is an example certificate only and may not be the lot that you receive.

Produits recommandés

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302
• Conseils de prudence: P301 + P312 + P330
• Classification des risques: Acute Tox. 4 Oral
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 321.8 °F - closed cup
• Point d'éclair (°C): 161 °C - closed cup