P3502

Phloroglucinol

Used to detect the presence of wood fiber.

• Synonyme(s) : 1,3,5-Trihydroxybenzene
• Formule empirique (notation de Hill): C₆H₆O₃
• Numéro CAS: 108-73-6
• Poids moléculaire : 126.11
• Numéro Beilstein : 1341907
• Numéro CE : 203-611-2
• Numéro MDL: MFCD00002286
• Code UNSPSC : 12171500
• ID de substance PubChem : 24898417
• Nomenclature NACRES : NA.47

Propriétés

• Niveau de qualité: 100
• Forme: powder or crystals
• Pf: 215-220 °C
• Solubilité: ethanol: 50 mg/mL (clear to hazy)
• Application(s): diagnostic assay manufacturing; hematology; histology
• Température de stockage: room temp
• Chaîne SMILES: Oc1cc(O)cc(O)c1
• InChI: 1S/C6H6O3/c7-4-1-5(8)3-6(9)2-4/h1-3,7-9H
• Clé InChI: QCDYQQDYXPDABM-UHFFFAOYSA-N

Description

Description générale

Phloroglucinol (phlo) is a phenol derivative that shows a cytoprotective effect from oxidative damage by enhancing the activity of cellular catalase. It can also be used to prepare synthetic analogs of A-type proanthocyanidins (PACs) such as 2,8-dioxabicyclo[3.3.1]nonane derivatives by reacting with the corresponding flavylium salts. Phlo can react with benzaldehyde derivatives to form phloroglucinol-based microporous polymeric organic frameworks (phlo-POF) with potential applications in ion exchange and gas adsorption.

Phloroglucinol is an antispasmodic and a derivative of phenol.

Application

Phloroglucinol has been used to prevent hyperhydricity by promoting the lignification of shoots. It has also been used in PG (phloroglucinol)-sucrose treatments for the growth and development of in vitro derived shoot tips. Phloroglucinol has been used to stain root sections. It has also been used to stain plant sections to identify plant materials like lignin.

Phloroglucinol has been used to stain root sections. It has also been used to stain plant sections to identify plant materials like lignin.

Actions biochimiques/physiologiques

Phloroglucinol displays antispasmodic activity. It is a trihydroxybenzene with antithrombotic, profibrinolytic, antimicrobial, antimalarial, cancer chemopreventive, anti-HIV, and anti-leishmanial activities. Phloroglucinol (PG) is a biosynthetic precursor of the 2,4-diacetylphloroglucinol (DAPG) an antibiotic against soil-borne diseases. Phloroglucinol is a useful intermediate because it is polyfunctional.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H317,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)