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O5380

Supelco

Oxethazaine

analytical standard

Synonyme(s) :

2-Hydroxyethyliminobis(N-[α,α-dimethylphenethyl]-N-methylacetamide), Oxetacaine

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About This Item

Formule empirique (notation de Hill):
C28H41N3O3
Numéro CAS:
126-27-2
Poids moléculaire :
467.64
Numéro CE :
204-780-5
Numéro MDL:
MFCD00079202
Code UNSPSC :
41116107
ID de substance PubChem :
329818914
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

200

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Format

neat

Chaîne SMILES 

CN(C(=O)CN(CCO)CC(=O)N(C)C(C)(C)Cc1ccccc1)C(C)(C)Cc2ccccc2

InChI

1S/C28H41N3O3/c1-27(2,19-23-13-9-7-10-14-23)29(5)25(33)21-31(17-18-32)22-26(34)30(6)28(3,4)20-24-15-11-8-12-16-24/h7-16,32H,17-22H2,1-6H3

Clé InChI

FTLDJPRFCGDUFH-UHFFFAOYSA-N

Description générale

Oxethazaine is a topical anesthetic, administered as an antacid for treating pain associated with duodenal ulcer, esophagitis and gastritis.

Application

Oxethazaine may be used as an analytical reference standard for the quantification of the analyte in biological samples using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
048F0668

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

T Takagi et al.
The American journal of physiology, 255(4 Pt 1), G522-G528 (1988-10-01)
Celiac and superior mesenteric arterial blood flows were measured simultaneously in conscious beagle dogs. The responses to food were completely different between the two arteries. Celiac flow increased quickly to 180-200% of the control 2 min after food but started
Y Masuda et al.
Japanese journal of pharmacology, 70(3), 243-252 (1996-03-01)
Alteration of hepatic microcirculation and its effects on hepatic metabolism were examined using oxethazaine (OXZ). The infusion of OXZ into isolated perfused livers rapidly increased the portal perfusion pressure (PP) and inhibited oxygen (O2) uptake, which was followed by a
Y Masuda et al.
Biochemical pharmacology, 53(12), 1779-1787 (1997-06-15)
We previously reported that, in isolated perfused rat livers in a constant flow system, oxethazaine (OXZ) rapidly increased portal pressure (PP) accompanied by inhibition of oxygen uptake and the subsequent metabolic effects. In this study, hemodynamic changes were studied by
Claire Barber et al.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 15(4), 427-440 (2006-11-30)
GOAL OF THE WORK: Oral mucositis (OM) is a functionally destructive complication of aggressive head and neck cancer therapy, often resulting in intense pain, an inability to eat and drink and secondary malnutrition and dehydration. The barrier-forming properties of Gelclair
G J Anthone et al.
American journal of surgery, 163(1), 150-156 (1992-01-01)
A signal for meal-induced absorption originates from the small intestine and is transmitted to a luminally excluded segment of the proximal jejunum (Thiry-Vella [TV] fistula). Using intraluminal topical anesthesia with oxethazaine, this study assessed the role of intestinal neural pathways
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