O0290000

Oxymetazoline hydrochloride

European Pharmacopoeia (EP) Reference Standard

• Synonyme(s) : 2-(3-Hydroxy-2,6-dimethyl-4-t-butylbenzyl)-2-imidazoline hydrochloride
• Formule empirique (notation de Hill): C₁₆H₂₄N₂O · HCl
• Numéro CAS: 2315-02-8
• Poids moléculaire : 296.84
• Numéro MDL: MFCD00058147
• Code UNSPSC : 41116107
• ID de substance PubChem : 329818837
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: pharmaceutical primary standard
• Famille d'API: oxymetazoline
• Fabricant/nom de marque: EDQM
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Température de stockage: 2-8°C
• Chaîne SMILES: Cl.Cc1cc(c(O)c(C)c1CC2=NCCN2)C(C)(C)C
• InChI: 1S/C16H24N2O.ClH/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14;/h8,19H,6-7,9H2,1-5H3,(H,17,18);1H
• Clé InChI: BEEDODBODQVSIM-UHFFFAOYSA-N
• Informations sur le gène: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

Description

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Oxymetazoline hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Actions biochimiques/physiologiques

Oxymetazoline hydrochloride is a partial α_2A-adrenoceptor agonist; agonist at 5-HT_1A, 5-HT_1B, and 5-HT_1D serotonin receptors. It is a mixed agonist-antagonist at 5-HT_1C serotonin receptors.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Informations sur la sécurité

• Pictogrammes: GHS05,GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H300 + H330 - H318 - H412
• Conseils de prudence: P260 - P264 - P273 - P280 - P304 + P340 + P310 - P305 + P351 + P338
• Classification des risques: Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Chronic 3 - Eye Dam. 1
• Code de la classe de stockage: 6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3