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C2250000

Clindamycine hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

(7S)-7-Chloro-7-désoxylincomycine hydrochloride, Cléocine

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About This Item

Formule empirique (notation de Hill):
C18H33ClN2O5S · HCl
Numéro CAS:
21462-39-5
Poids moléculaire :
461.44
Numéro Beilstein :
4070786
Numéro MDL:
MFCD07793327
Code UNSPSC :
41116107
ID de substance PubChem :
329774985
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

clindamycin

Fabricant/nom de marque

EDQM

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

Cl.CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@H](C)Cl)C2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O

InChI

1S/C18H33ClN2O5S.ClH/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H/t9-,10+,11-,12+,13-,14+,15+,16+,18+;/m0./s1

Clé InChI

AUODDLQVRAJAJM-XJQDNNTCSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Clindamycin hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Actions biochimiques/physiologiques

La clindamycine est un antibiotique semi-synthétique du type lincosamide préparé à partir de la lincomycine. Elle inhibe la synthèse des protéines bactériennes par des interactions du type liaisons hydrogène avec le composant ARNr 23S de la sous-unité ribosomale 50S, induisant ainsi la dissociation du complexe peptidyl-ARNt. Elle a une activité antibactérienne contre les coques à Gram positif et une activité antiprotozoaire contre Taxoplasma.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Antibiotique antibactérien et antiprotozoaire de la classe des lincosamides.
Sales restrictions may apply.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H317,H319,H362

Classification des risques

Eye Irrit. 2 - Lact. - Skin Sens. 1

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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