46738

Spectinomycin dihydrochloride pentahydrate

VETRANAL^®, analytical standard

• Formule empirique (notation de Hill): C₁₄H₂₄N₂O₇ · 2HCl · 5H₂O
• Numéro CAS: 22189-32-8
• Poids moléculaire : 495.35
• Beilstein: 5684150
• Numéro CE : 244-554-3
• Numéro MDL: MFCD00150886
• Code UNSPSC : 41116107
• ID de substance PubChem : 329757229
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: analytical standard
• Niveau de qualité: 100
• Gamme de produits: VETRANAL^®
• Durée de conservation: limited shelf life, expiry date on the label
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Solubilité: H₂O: soluble at
• Spectre d'activité de l'antibiotique: Gram-negative bacteria; Gram-positive bacteria
• Application(s): clinical testing
• Format: neat
• Mode d’action: protein synthesis | interferes
• Température de stockage: 2-8°C
• Chaîne SMILES: Cl[H].Cl[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H][C@@]12O[C@H](C)CC(=O)[C@]1(O)O[C@]3([H])[C@@H](NC)[C@@H](O)[C@@H](NC)[C@H](O)[C@@]3([H])O2
• InChI: 1S/C14H24N2O7.2ClH.5H2O/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14;;;;;;;/h5,7-13,15-16,18-20H,4H2,1-3H3;2*1H;5*1H2/t5-,7-,8+,9+,10+,11-,12-,13+,14+;;;;;;;/m1......./s1
• Clé InChI: DCHJOVNPPSBWHK-UXXUFHFZSA-N

Description

Description générale

Chemical structure: aminoglycoside

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Spectinomycin dihydrochloride pentahydrate may be used as a reference standard for the determination of spectinomycin in bovine milk samples by liquid chromatography with electrochemical detection.

Spectinomycin is an aminocyclitol antibiotic derived from Streptomyces spectabilis. It has been shown to have a wide variety of uses, including treating acute gonorrheal urethritis and cervictis, to mark cell layers to monitor cell fate during leaf development, as a selection marker in plant related transformation systems for plant cells containing the marker gene Spcr, to study respiratory tract infections of cattle caused by Pasteurella multocida and Mannheimia haemolytica, and to generate plants deficient for the plastid-encoded RNA polymerase on MS-agar media. Spectinomycin also has use in amplification of low copy number plasmid carrying replicons. It is recommended for use in cell culture applications at 7.5-20 mg/L.

Attention

Solutions can be stored at 2-8°C for several weeks or at -20°C for more extended periods.

Notes préparatoires

Stock solutions should be prepared at 10 mg/mL in water and filter sterilized.

Informations légales

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)