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35404

Supelco

5-Hydroxymebendazole

VETRANAL®, analytical standard

Synonyme(s) :

Methyl 5-[(RS)-α-hydroxybenzyl]-1H-benzimidazole-2-carbamate

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About This Item

Formule empirique (notation de Hill):
C16H15N3O3
Numéro CAS:
60254-95-7
Poids moléculaire :
297.31
Numéro Beilstein :
4537623
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

100

Gamme de produits

VETRANAL®

Durée de conservation

limited shelf life, expiry date on the label

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

forensics and toxicology
pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

COC(=O)Nc1nc2ccc(cc2[nH]1)C(O)c3ccccc3

InChI

1S/C16H15N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9,14,20H,1H3,(H2,17,18,19,21)

Clé InChI

IIQKUGXEGMZCLE-UHFFFAOYSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Produits recommandés

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Informations légales

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

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Certificats d'analyse (COA)

Lot/Batch Number
BCCK4274
BCCG1851
BCCC7049
BCCB5908
BCBZ6936

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

S Gupta et al.
Indian journal of experimental biology, 29(7), 645-648 (1991-07-01)
Methyl 5(6)-(alpha-hydroxyphenylmethyl) benzimidazole-2- carbamate, a metabolite of mebendazole, was evaluated against metamorphic forms of Ancylostoma ceylanicum in hamsters, Nippostrongylus brasiliensis in rats and cysticercoids of Hymenolepis nana in grain beetles. The test compound offered better action than mebendazole except against
Anthelmintic activity of methyl 5(6)-(alpha-hydroxyphenyl methyl) benzimidazole-2-carbamate, a metabolite of mebendazole.
S Gupta et al.
Indian journal of experimental biology, 25(12), 871-873 (1987-12-01)
E G Iosifidou et al.
Drug metabolism and disposition: the biological fate of chemicals, 25(3), 317-320 (1997-03-01)
Mebendazole (MBZ) is extensively used in eel culture for treatment of Pseudodactylogyrus spp. infections. This use may lead to residues of MBZ in eel tissues. Consequently, the residue profile of MBZ in eel after treatment with the drug is of
H De Ruyck et al.
The Analyst, 126(12), 2144-2148 (2002-01-30)
A quantitative liquid chromatography-electrospray tandem mass spectrometry method for the determination of mebendazole and its hydrolysed and reduced metabolites in sheep liver has been developed and validated. The benzimidazole substances were extracted with ethyl acetate after the sample mixture had
B Oosterhuis et al.
Therapeutic drug monitoring, 6(2), 215-220 (1984-01-01)
A sensitive method is described for the simultaneous determination of mebendazole and hydroxymebendazole using flubendazole as an internal standard. The analytes were isolated with a single chloroform extraction from 1.0 ml of alkalinized plasma or cyst liquid samples. Separation and
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