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34091

Supelco

Flubendazol

VETRANAL®, analytical standard

Synonyme(s) :

Flumoxanal, Methyl [5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate

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About This Item

Formule empirique (notation de Hill):
C16H12FN3O3
Numéro CAS:
31430-15-6
Poids moléculaire :
313.28
Numéro CE :
250-624-4
Numéro MDL:
MFCD00871999
Code UNSPSC :
41116107
ID de substance PubChem :
329754807
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

100

Gamme de produits

VETRANAL®

Durée de conservation

limited shelf life, expiry date on the label

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

forensics and toxicology
pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3ccc(F)cc3

InChI

1S/C16H12FN3O3/c1-23-16(22)20-15-18-12-7-4-10(8-13(12)19-15)14(21)9-2-5-11(17)6-3-9/h2-8H,1H3,(H2,18,19,20,22)

Clé InChI

CPEUVMUXAHMANV-UHFFFAOYSA-N

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Catégories apparentées

Description générale

Flubendazol is a broad spectrum anthelmintic, which belongs to the class of compounds known as benzimidazoles. It can be widely used in veterinary and human medicine. It mainly finds applications in deworming poultry, swine, dogs and cats.
Flubendazol is an injectable benzimidazole drug; though it is poorly absorbed it is quite effective in the treatment of trycocephalus, ascaris and oxyuriasis in both children and adults.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
VETRANAL® analytical standard can be used in the liquid chromatography coupled to mass spectrometry (LC-MS/MS) procedure, performed for the analysis of macrocyclic lactones in milk.

Informations légales

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
BCCD3951
BCBW0774

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Jung-Min Lee et al.
The Korean journal of parasitology, 49(3), 273-275 (2011-11-11)
Praziquantel is the drug of choice for clonorchiasis. Since clonorchiasis is endemic in most river basins, praziquantel has been widely used for 30 years in Korea. A 54-year-old Korean woman suffered from hypersensitive reactions, such as nausea, dyspnea, rash, and
J Boes et al.
Veterinary parasitology, 172(3-4), 269-276 (2010-06-15)
Scientific investigations of production losses in pigs due to roundworms are rarely conducted in commercial farms, despite the fact that this information is needed to decide whether anthelmintic treatment is cost-effective or not. Therefore, the aim of our study was
V Krízová et al.
Journal of veterinary pharmacology and therapeutics, 32(6), 606-612 (2010-05-07)
Flubendazole (FLU) is indicated for control of helminthoses in pig and avian species (monogastric animals) and its corresponding pharmacokinetics are well known. The information on FLU's pharmacokinetic behavior in animal species with forestomach (ruminants) has been limited although the use
S Squires et al.
Veterinary parasitology, 185(2-4), 352-354 (2011-10-26)
The efficacy of a commercially available flubendazole-based product and a commercially available herbal product were compared against three species of helminth parasites of chickens: Ascaridia galli, Heterakis gallinarum and Capillaria spp. A total of 48 naturally infected chickens were used
Hana Bártíková et al.
Parasitology, 139(6), 809-818 (2012-02-09)
The drug-metabolizing enzymes of some helminths can deactivate anthelmintics and therefore partially protect helminths against these drugs' toxic effect. The aim of our study was to assess the activity of the main drug-metabolizing enzymes and evaluate the metabolism of selected
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