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114472

Sigma-Aldrich

Cresol red

indicator grade, Dye content 95 %

Synonyme(s) :

o-Cresolsulfonphthalein

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About This Item

Formule empirique (notation de Hill):
C21H18O5S
Numéro CAS:
1733-12-6
Poids moléculaire :
382.43
Numéro Beilstein :
343399
Numéro CE :
217-064-2
Numéro MDL:
MFCD00005878
Code UNSPSC :
12171500
ID de substance PubChem :
24847173
Nomenclature NACRES :
NA.47

Qualité

indicator grade

Niveau de qualité

200

Forme

powder or crystals

Composition

Dye content, 95%

Technique(s)

titration: suitable

Couleur

red-brown

pH

7.2-8.8, yellow to red

Plage de pH utile

1.8-2.0, orange to yellow(acid)
7.0-8.8, yellow to violet(alkaline)

Pf

290 °C

Densité

0.998 g/cm3

λmax

367 nm (2nd)
570 nm

Application(s)

diagnostic assay manufacturing
hematology
histology

Température de stockage

room temp

Chaîne SMILES 

Cc1cc(ccc1O)C2(OS(=O)(=O)c3ccccc23)c4ccc(O)c(C)c4

InChI

1S/C21H18O5S/c1-13-11-15(7-9-18(13)22)21(16-8-10-19(23)14(2)12-16)17-5-3-4-6-20(17)27(24,25)26-21/h3-12,22-23H,1-2H3

Clé InChI

OBRMNDMBJQTZHV-UHFFFAOYSA-N

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Description générale

Cresol Red, also known as o-cresol red, belongs to the phthalein and sulphonphthalein group of dyes. Cresol red changes color from orange to yellow at pH between 0.2-1.8 and yellow to violet at pH between 7.0-8.8. In alkaline solutions, cresol red is present as a hydrophilic dianion. The dianion is small and is violet in color, possessing a larger conjugated system than the yellow hydroxyquinone.

Application

Cresol Red is a widely used pH indicator for routine pH assessments like microbial culture media preparations. In addition, Cresol red is a suitable constituent of PCR reagent systems. Cresol Red is used as a tracking dye in DNA, RNA (agarose), and protein (polyacrylamide) electrophoresis.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
BCCG0571
BCCF3167
BCCC8198
BCCB7394
BCBX0336

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Atsushi Seki et al.
Analytica chimica acta, 582(1), 154-157 (2007-03-28)
Novel spectroscopic sensor based on a hetero-core structured fiber optic is described in this paper. The hetero-core structured fiber optic consists of multi mode fibers and a short piece of single mode fiber which was inserted in the multi mode
Paula C A Jerónimo et al.
The Analyst, 130(8), 1190-1197 (2005-07-16)
An optical biosensor based on immobilised carbonic anhydrase and its application to the determination of the anti-glaucoma agent acetazolamide by enzyme inhibition measurements, is described. The enzyme and a pH indicator dye, cresol red, were physically immobilised in overlapped sol-gel
Berthold Borucki et al.
Biochemistry, 41(31), 10026-10037 (2002-07-31)
We studied the kinetics of proton uptake and release by photoactive yellow protein (PYP) from Ectothiorhodospira halophila in wild type and the E46Q and E46A mutants by transient absorption spectroscopy with the pH-indicator dyes bromocresol purple or cresol red in
M Swati et al.
Analytica chimica acta, 676(1-2), 68-74 (2010-08-31)
An optical biosensing scheme based on urease encapsulated calcium alginate microspheres which are coated with polyelectrolyte nanofilms predominantly composed of cresol red (CR) dye is demonstrated in this paper. The dye molecules within the nanofilms are deposited via the layer-by-layer
K Horie et al.
Analytical biochemistry, 137(1), 80-87 (1984-02-01)
A highly sensitive quantitative method was developed to detect protons released or taken up upon ligand binding. A small change in pH due to proton release or uptake was detected by measuring the difference in the absorbance of a pH
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