03951
N-Ethylformamide
≥99.0% (GC)
Synonyme(s) :
N-Formylethylamine
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About This Item
Formule linéaire :
HCONHC2H5
Numéro CAS:
Poids moléculaire :
73.09
Numéro Beilstein :
1737860
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352100
ID de substance PubChem :
Nomenclature NACRES :
NA.22
Niveau de qualité
100
500
Pureté
≥99.0% (GC)
Forme
liquid
Indice de réfraction
n20/D 1.432
Point d'ébullition
202-204 °C
Densité
0.950 g/mL at 20 °C (lit.)
Chaîne SMILES
CCNC=O
InChI
1S/C3H7NO/c1-2-4-3-5/h3H,2H2,1H3,(H,4,5)
Clé InChI
KERBAAIBDHEFDD-UHFFFAOYSA-N
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Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
235.4 °F - closed cup
Point d'éclair (°C)
113 °C - closed cup
Équipement de protection individuelle
Eyeshields, Gloves
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P Kestell et al.
The Journal of pharmacology and experimental therapeutics, 240(1), 265-270 (1987-01-01)
The hepatotoxicity and metabolism of the following close analogs of the hepatotoxic antitumor agent N-methylformamide (NMF) were investigated in CBA/CA mice: N-ethylformamide (NEF), dimethylformamide (DMF), formamide and N-methylacetamide (NMA). Apart from NMF only NEF was potently hepatotoxic as measured by
S P Langdon et al.
Toxicology, 43(3), 239-249 (1987-03-01)
The induction of terminal differentiation in tumour cells represents a possible therapeutic strategy for treating cancer. The alkylformamides are 1 group of experimental compounds which have been shown to induce terminal differentiation in human HL-60 leukemia and murine Friend erythroleukemia
M R Del Carratore et al.
Environmental and molecular mutagenesis, 36(2), 97-104 (2000-10-03)
A cDNA coding for rat cytochrome P450 2E1 was cloned into the multicopy vector pYeDP60 and expressed in haploid RSY6 and diploid RS112 yeast strains of Saccharomyces cerevisiae under control of the GAL10-CYC1 promoter. Spectral and catalytic properties of the
Gil-Soo Han et al.
The Journal of biological chemistry, 283(29), 20443-20453 (2008-05-07)
The Saccharomyces cerevisiae DGK1 gene encodes a diacylglycerol kinase enzyme that catalyzes the formation of phosphatidate from diacylglycerol. Unlike the diacylglycerol kinases from bacteria, plants, and animals, the yeast enzyme utilizes CTP, instead of ATP, as the phosphate donor in
H Cross et al.
Chemical research in toxicology, 3(4), 357-362 (1990-07-01)
Hepatotoxic formamides such as N-methylformamide (NMF) and N,N-dimethylformamide (DMF) are metabolized in vivo to N-acetyl-S-(N-methylcarbamoyl)cysteine via oxidation at the formyl carbon, which yields a reactive intermediate. The hypothesis was tested that this biotransformation route can be studied in vitro with
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