SCT038

BioTracker Orange OH and HClO Dye

Live cell imaging probe to detect hydroxy radical (OH) or hypochlorous acid (HClO) in live cells.

• Code UNSPSC : 12352207
• Nomenclature NACRES : NA.47

Propriétés

• Forme: lyophilized
• Application(s): cell analysis
• Méthode de détection: fluorometric

Description

Description générale

Reactive oxygen species (ROS) are important mediators in a variety of biological and pathological events. For example, ROS generated in mitochondria play important roles in the modulation of signal transduction cascades and transcription factors. However, oxidative stress due to excessive generation of ROS is implicated in many human diseases, including acute and chronic inflammatory processes, ischemic stroke, diabetes, sepsis, ischemia-reperfusion injury, atherosclerosis, and neurodegenerative disorders.BioTracker Orange OH and HClO Dye is an orange fluorescent probe to detect hydroxy radical (・OH) or hypochlorous acid (HClO) in live-cell imaging. It can detect -OH and HClO among other reactive oxygen species (O2^-, H₂O₂, NO, ONOO^-). Its nearly red fluorescence spectrum allows multicolor imaging with green (ex. GFP, FITC) and blue (ex. Hoechst 33342) fluorophores. Because of its positive charge, OxiORANGE tends to localize within mitochondria. It has high photostability and is suitable for time-lapse imaging of intracellular hROS generation.Spectral Properties:Absorbance (max): 553mEmission (max): 577nmResearch Category:Live Cell Dye

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable