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Merck
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Key Documents

Autres documents

OP180

Sigma-Aldrich

Anti-Noxa Mouse mAb (114C307)

liquid, clone 114C307, Calbiochem®

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About This Item

Code UNSPSC :
12352203

Source biologique

mouse

Niveau de qualité

100

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

114C307, monoclonal

Forme

liquid

Contient

≤0.1% sodium azide as preservative

Espèces réactives

human

Fabricant/nom de marque

Calbiochem®

Conditions de stockage

OK to freeze
avoid repeated freeze/thaw cycles

Isotype

IgG1

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... PMAIP1(5366)

Description générale

Purified mouse monoclonal antibody. Recognizes the ~11 kDa Noxa protein.
Recognizes the ~11 kDa Noxa protein in RL-7 cells.
This Anti-Noxa Mouse mAb (114C307) is validated for use in Immunoblotting for the detection of Noxa.

Immunogène

Human
a recombinant protein consisting of human Noxa fused to GST

Application


Immunoblotting (1-2 g/ml, chemiluminescence)

Conditionnement

Please refer to vial label for lot-specific concentration.

Avertissement

Toxicity: Standard Handling (A)

Forme physique

In PBS, 0.05% BSA.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C;)

Remarque sur l'analyse

Negative Control
Normal mouse serum
Positive Control
RL-7 cell lysate

Autres remarques

Antibody should be titrated for optimal results in individual system.
Oda, E., et al. 2000. Science288, 1053.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Min Ji Seo et al.
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Gambogic acid (GA), a xanthonoid extracted from the resin of the tree, Garcinia hanburyi, was recently shown to exert anticancer activity in multiple studies, but the underlying action mechanism remains unclear. Here, we show that GA induces cancer cell death
Mateus Milani et al.
Cell death discovery, 5, 117-117 (2019-07-26)
Maintenance of mitochondrial integrity is critical for normal cellular homoeostasis. Most cells respond to stress stimuli and undergo apoptosis by perturbing mitochondrial structure and function to release proteins, such as cytochrome c, which are essential for the execution of the
Nabanita Mukherjee et al.
Cancers, 12(8) (2020-08-09)
There is an urgent need to develop treatments for patients with melanoma who are refractory to or ineligible for immune checkpoint blockade, including patients who lack BRAF-V600E/K mutations. This is often the case in patients diagnosed with rare melanoma subtypes
Santi Rello-Varona et al.
Scientific reports, 9(1), 3816-3816 (2019-03-09)
Soft-tissue sarcomas (STS) are an uncommon and heterogeneous group of malignancies that result in high mortality. Metastatic STS have very bad prognosis due to the lack of effective treatments. Dinaciclib is a model drug for the family of CDK inhibitors.
Tao Hu et al.
Molecular carcinogenesis, 58(1), 42-54 (2018-09-06)
Increasing evidence suggests that deubiquitinase USP7 participates in tumor progression by various mechanisms and serves as a potential therapeutic target. However, its expression and role in esophageal cancer remains elusive; the anti-cancer effect by targeting USP7 still needs to be
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