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MABS2156

Sigma-Aldrich

Anti-Thrombomodulin Antibody, clone 1009

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Forme d'anticorps

purified antibody

Clone

1009
monoclonal

Produit purifié par

using protein G

Espèces réactives

human, rat, mouse

Concentration

(Please refer to lot specific datasheet.)

Technique(s)

flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
radioimmunoassay: suitable
western blot: suitable

Isotype

IgG1κ

Numéro d'accès UniProt

Mode d’action

| inhibits

Description générale

Recombinant fragment corresponding to 241 amino acids corresponding to six EGF repeats from human Thrombomodulin.

Spécificité

Clone 1009 is a mouse monoclonal antibody that detects Thrombomodulin.

Application

Immunohistochemistry (Paraffin) Analysis: A 1:50 dilution from a representative lot detected Thrombomodulin in human tonsil tissue sections.

ELISA Analysis: A representative lot detected Thrombomodulin in ELISA applicaitons (Woodley-Cook, J., et. al. (2006). Mol Cancer Ther. 5(12):3303-11).

Radioimmunoassay Analysis: A representative lot detected Thrombomodulin in Radioimmunoassay applications (Woodley-Cook, J., et. al. (2006). Mol Cancer Ther. 5(12):3303-11).

Inhibits Activity/Function Analysis: A representative lot of this blocked thrombin binding and reduced Protein C activation (Stearns-Kurosawa, D.J., et. al. (1996). Proc Natl Acad Sci USA. 93(19):10212-6).

Flow Cytometry Analysis: A representative lot detected Thrombomodulin in Flow Cytometry applications (Stearns-Kurosawa, D.J., et. al. (1996). Proc Natl Acad Sci USA. 93(19):10212-6; Woodley-Cook, J., et. al. (2006). Mol Cancer Ther. 5(12):3303-11).

Western Blotting Analysis: A representative lot detected Thrombomodulin in Western Blotting applications. (Xu, J., et. al. (1999). J Biol Chem. 274(10):6704-10; Woodley-Cook, J., et. al. (2006). Mol Cancer Ther. 5(12):3303-11).

Immunocytochemistry Analysis: A representative lot detected Thrombomodulin in Immunocytochemistry applications (Campbell, J.E., et. al. (2010). Blood. 116(26):6082-91).

Immunohistochemistry (Paraffin) Analysis: A representative lot detected Thrombomodulin in Immunohistochemistry applications (Trotman, W.E., et. al. (2011). Histochem Cell Biol. 135(2):141-52).

Qualité

Evaluated by Immunohistochemistry (Paraffin) in human placenta tissue sections.

Immunohistochemistry (Paraffin) Analysis: A 1:50 dilution of this antibody detected Thrombomodulin in human placenta tissue sections.

Propriétés physiques

~60.33 kDa calculated.

Forme physique

Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Autres remarques

Human, Rat.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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