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Key Documents

MAB5228

Sigma-Aldrich

Anti-Amyloid Precursor Protein Antibody, Secretory, clone OM84

clone OM84, Chemicon®, from mouse

Synonyme(s) :

APP

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

OM84, monoclonal

Espèces réactives

human

Fabricant/nom de marque

Chemicon®

Technique(s)

ELISA: suitable
western blot: suitable

Isotype

IgG2aκ

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... APP(351)

Spécificité

Reacts with secretory amyloid precursor protein (sAPP), but not with Amyloid-Beta protein 1-40.

Immunogène

Amyloid Precursor Protein (APP) secreted by the EJ-1 bladder carcinoma cell line.
Epitope: Secretory

Application

Anti-Amyloid Precursor Protein Antibody, Secretory, clone OM84 detects level of Amyloid Precursor Protein & has been published & validated for use in ELISA & WB.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Western blot: 10 μg/mL ELISA: 1 μg/mL

Optimal working dilutions must be determined by end user.

Forme physique

Format: Purified
Protein A Purified mouse immunoglobulin in 10 mM sodium phosphate buffer (pH 7.4), 0.15 M NaCl, and 0.1% sodium azide as a preservative..
Protein A purified

Stockage et stabilité

Maintain frozen at -70°C or below in undiluted aliquots for up to 12 months, avoid repeated freeze/thaw cycles.

Remarque sur l'analyse

Control
Brain

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Dual roles of the transmembrane protein p23/TMP21 in the modulation of amyloid precursor protein metabolism
Vetrivel, Kulandaivelu S, et al.
Mol. Neurodegener., 2, 4-4 (2007)
A novel actin-binding domain on Slo1 calcium-activated potassium channels is necessary for their expression in the plasma membrane.
Zou, S; Jha, S; Kim, EY; Dryer, SE
Molecular Pharmacology null
Christine Römer et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(20), 7777-7794 (2015-05-23)
Stroke-induced immunodepression (SIDS) is an essential cause of poststroke infections. Pharmacological inhibition of SIDS appears promising in preventing life-threatening infections in stroke patients. However, SIDS might represent an adaptive mechanism preventing autoreactive immune responses after stroke. To address this, we
Ellen Sapp et al.
Neurobiology of disease, 141, 104950-104950 (2020-05-23)
Molecular changes at synapses are thought to underly the deficits in motor and cognitive dysfunction seen in Huntington's disease (HD). Previously we showed in synaptosome preparations age dependent changes in levels of selected proteins examined by western blot assay in

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