MAB2258
Anti-Syntaxin-3 Antibody, clone 1-146
clone 1-146, from mouse
Synonyme(s) :
syntaxin 3, syntaxin 3A
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
mouse
Niveau de qualité
Forme d'anticorps
purified antibody
Type de produit anticorps
primary antibodies
Clone
1-146, monoclonal
Espèces réactives
human, rat
Réactivité de l'espèce (prédite par homologie)
mouse
Technique(s)
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
Isotype
IgG1κ
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... STX3(6809)
rat ... Stx3(81802)
Catégories apparentées
Description générale
Syntaxin-3, also known as Stx3, is a member of the SNARE family which are complexes involved in membrane fusion. Syntaxin-3 is expressed in epithelial cells and is found apically in MDCK and Caco-2 cells (1).
Spécificité
This antibody recognizes Syntaxin-3.
Immunogène
GST-tagged recombinant protein corresponding to residues contained within rat Syntaxin-3.
Application
Detect Syntaxin-3 using this Anti-Syntaxin-3 Antibody, clone 1-146 validated for use in WB, IP, IH.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Synapse & Synaptic Biology
Synapse & Synaptic Biology
Qualité
Evaluated by Western Blot in rat brain tissue lysate.
Western Blot Analysis: : 0.5 µg/mL dilution of this antibody detected Syntaxin-3 on 15 µg of rat brain tissue lysate.
Western Blot Analysis: : 0.5 µg/mL dilution of this antibody detected Syntaxin-3 on 15 µg of rat brain tissue lysate.
Description de la cible
Approx. 33 kDa
Forme physique
Format: Purified
Protein G Purified
Purified mouse monoclonal in buffer containing 0.1 M Tris-glycine, pH 7.4, 150 mM NaCl with 0.05% NaN3.
Stockage et stabilité
Maintain refrigerated at 2-8°C for 1 year from date of receipt.
Remarque sur l'analyse
Control
Rat brain tissue lysate
Rat brain tissue lysate
Autres remarques
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Daniëlle Rianne José Verboogen et al.
eLife, 6 (2017-05-20)
SNARE proteins play a crucial role in intracellular trafficking by catalyzing membrane fusion, but assigning SNAREs to specific intracellular transport routes is challenging with current techniques. We developed a novel Förster resonance energy transfer-fluorescence lifetime imaging microscopy (FRET-FLIM)-based technique allowing
Adrian J Giovannone et al.
Molecular biology of the cell, 28(21), 2843-2853 (2017-08-18)
Syntaxin 3 (Stx3), a SNARE protein located and functioning at the apical plasma membrane of epithelial cells, is required for epithelial polarity. A fraction of Stx3 is localized to late endosomes/lysosomes, although how it traffics there and its function in
Hiroshi Gomi et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 65(11), 637-653 (2017-09-16)
The comparative structure and expression of salivary components and vesicular transport proteins in the canine major salivary glands were investigated. Histochemical analysis revealed that the morphology of the five major salivary glands-parotid, submandibular, polystomatic sublingual, monostomatic sublingual, and zygomatic glands-was
Poppy Datta et al.
The Journal of biological chemistry, 294(50), 19119-19136 (2019-11-07)
Mutations in the centrosomal protein 290 (CEP290) gene cause various ciliopathies involving retinal degeneration. CEP290 proteins localize to the ciliary transition zone and are thought to act as a gatekeeper that controls ciliary protein trafficking. However, precise roles of CEP290
Poppy Datta et al.
PloS one, 16(5), e0246358-e0246358 (2021-05-08)
Nephrocystin (NPHP1) is a ciliary transition zone protein and its ablation causes nephronophthisis (NPHP) with partially penetrant retinal dystrophy. However, the precise requirements of NPHP1 in photoreceptors are not well understood. Here, we characterize retinal degeneration in a mouse model
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