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Merck
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Key Documents

MAB1955

Sigma-Aldrich

Anti-Integrin α4 Antibody, clone P4C2

ascites fluid, clone P4C2, Chemicon®

Synonyme(s) :

CD49d

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

Forme d'anticorps

ascites fluid

Type de produit anticorps

primary antibodies

Clone

P4C2, monoclonal

Espèces réactives

human

Fabricant/nom de marque

Chemicon®

Technique(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable

Isotype

IgG3

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... ITGA4(3676)

Spécificité

alpha4 integrin. The alpha4beta1 integrin receptor recognizes an RGD-independent alternative adhesion site in the CS-1 region of fibronectin.

Application

Immunofluorescence and immunoprecipitation.

Inhibits attachment of hematopoeitic cells and T-lymphocytes but not fibroblasts to fibronectin; typical titer is >1:1,000

Aggregation of Jurkat cells to 1:1600 dilution
Research Category
Cell Structure
Research Sub Category
Integrins
This Anti-Integrin α4 Antibody, clone P4C2 is validated for use in IP, IH, FUNC for the detection of Integrin α4.

Liaison

Replaces: 04-1131

Forme physique

Liquid ascites containing sodium azide as a preservative.

Stockage et stabilité

Store at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Consulter la Bibliothèque de documents

Well plate-coupled microfluidic devices designed for facile image-based cell adhesion and transmigration assays.
Carolyn G Conant,Michael A Schwartz,Cristian Ionescu-Zanetti
Journal of Biomolecular Screening null
Huanqing Gao et al.
Biochemical and biophysical research communications, 491(1), 204-208 (2017-07-18)
Adipogenesis is a process of differentiation from preadipocyte into adipocyte, and is regulated by several transcription factors, including the peroxisome proliferator-activated receptor gamma (PPARγ) and the CCAAT-enhancer-binding protein alpha (C/EBPα). CD36 is a membrane protein which contributes to the metabolic
Identification and characterization of the T lymphocyte adhesion receptor for an alternative cell attachment domain (CS-1) in plasma fibronectin.
Wayner, E A, et al.
The Journal of cell biology, 109, 1321-1330 (1989)
Michelle B Chen et al.
Cancer research, 76(9), 2513-2524 (2016-03-19)
Tumor integrin β1 (ITGB1) contributes to primary tumor growth and metastasis, but its specific roles in extravasation have not yet been clearly elucidated. In this study, we engineered a three-dimensional microfluidic model of the human microvasculature to recapitulate the environment
Seung-Ki Min et al.
Cell death and differentiation, 25(2), 268-281 (2017-09-25)
Osteoporosis affects millions of people worldwide by promoting bone resorption and impairing bone formation. Bisphosphonates, commonly used agents to treat osteoporosis, cannot reverse the substantial bone loss that has already occurred by the time of diagnosis. Moreover, their undesirable side-effects

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