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Merck
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Key Documents

ABE480

Sigma-Aldrich

Anti-Centrin-2 Antibody

serum, from rabbit

Synonyme(s) :

Centrin-2, Caltractin isoform 1

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100

Forme d'anticorps

serum

Type de produit anticorps

primary antibodies

Clone

polyclonal

Espèces réactives

human, mouse, rat

Technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Numéro d'accès NCBI

NP_004335

Numéro d'accès UniProt

P41208

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... CETN2(1069)

Description générale

Centrin-2 is also called Caltractin isoform 1. Centrin-2 is involved in microtubule organization, structure and function, and is required for centriole duplication and spindle formation. Centrin-2 also has a role in regulating cytokinesis, genome stability and global genome nucleotide excision repair (GG-NER) as component of the XPC complex.

Immunogène

Recombinant protein corresponding to human Centrin-2.

Application

Anti-Centrin-2 Antibody is a highly specific rabbit polyclonal antibody, that targets Centrin & has been tested in western blotting, ICC, IHC & IP.
Immunocytochemistry Analysis: A representative lot from an independent laboratory detected Centrin-2 in MDCK cells (Koch, A., et al. (2010). Mol Biol Cell. 21(2):219-231.).

Immunohistochemistry Analysis: A representative lot from an independent laboratory detected Centrin-2 in wild type and galectin-3 null mouse kidney tissues (Koch, A., et al. (2010). Mol Biol Cell. 21(2):219-231.).

Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated Centrin-2 in MDCK cell lysate (Koch, A., et al. (2010). Mol Biol Cell. 21(2):219-231.).

Qualité

Evaluated by Western Blotting in Jurkat cell lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Centrin-2 in 10 µg of Jurkat cell lysate.

Description de la cible

~18 kDa observed. Uncharacterized band(s) may be observed in some cell lysates.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Annett Koch et al.
Molecular biology of the cell, 21(2), 219-231 (2009-11-20)
Galectin-3 is a beta-galactoside-binding protein widely expressed in all epithelia where it is involved in tissue homeostasis and cancer progression. We recently reported unique abnormalities in the identity of membrane domains in galectin-3 null mutant mice, suggesting that galectin-3 may
Juliette Azimzadeh et al.
The Journal of cell biology, 185(1), 101-114 (2009-04-08)
Centrin has been shown to be involved in centrosome biogenesis in a variety of eukaryotes. In this study, we characterize hPOC5, a conserved centrin-binding protein that contains Sfi1p-like repeats. hPOC5 is localized, like centrin, in the distal portion of human
Renee A Lopez et al.
Bio-protocol, 7(21), e2599-e2599 (2017-11-05)
Male gametes (spermatozoids) are the only motile cells produced during the life cycle of land plants. While absent from flowering and most cone-bearing plants, motile cells are found in less derived taxa, including bryophytes (mosses, liverworts and hornworts), pteridophytes (lycophytes

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