ABD85

Anti-PAX3/7BP Antibody

serum, from rabbit

• Synonyme(s) : PAX3 binding protein 1, PAX7 binding protein 1, GC-rich sequence DNA-binding factor 1
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: serum
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Espèces réactives: rat, mouse, human
• Technique(s): immunoprecipitation (IP): suitable; western blot: suitable
• Numéro d'accès UniProt: Q9Y5B6
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: mouse ... Paxbp1(67367)

Description

Description générale

In skeletal muscles, Pax7 uniquely marks muscle satellite cells and plays some important yet unknown functions at the perinatal stage. Pax3/7BP is a ubiquitously expressed nuclear protein, enriched in Pax7+ muscle precursor cells (MPCs), and serves as an indispensable adaptor for Pax7 to recruit the histone-3-lysine-4 (H3K4) methyltransferase (HMT) complex by bridging Pax7 and Wdr5. Recently, Wu et al. have established Pax3/7BP as an essential adaptor linking Pax3/7 with the H3K4 HMT to regulate the proliferation of muscle progenitor cells.

Immunogène

Recombinant protein corresponding to mouse PAX3/7BP.

Application

Anti-PAX3/7BP Antibody is an antibody against PAX3/7BP for use in western blotting & IP.

Research Category
Stem Cell Research

Research Sub Category
Muscle Physiology

Developmental Signaling

Qualité

Evaluated by Western Blot in a jurkat cell lysate.
Western Blot Analysis: A 1:1000 dilution of this antibody detected Pax3/7BP in a 10 µg jurkat cell lysate.

Description de la cible

~105 kDa observed. Uncharacterized bands may be observed in some lysate(s).

Forme physique

Unpurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1