ABC442

Anti-Cathepsin Z Antibody

from rabbit, purified by affinity chromatography

• Synonyme(s) : Cathepsin Z, Cathepsin P, Cathepsin X
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: human
• Technique(s): western blot: suitable
• Numéro d'accès NCBI: NP_001327
• Numéro d'accès UniProt: Q9UBR2
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... CTSZ(1522)

Description

Description générale

Cathepsin Z, also known as Cathepsin P, Cathepsin X, and encoded by the gene name CTSZ, is a member of the the peptidase C1 family. Cathepsin Z is a lysosomal cysteine proteinase that exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. Cathepsin Z is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis. At least two transcript variants of this gene have been found, but the full-length nature of only one of them has been determined.

Immunogène

Epitope: Near C-terminus

KLH-conjugated linear peptide corresponding to human Cathepsin Z near the C-terminus.

Application

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

This Anti-Cathepsin Z antibody is validated for use in Western Blotting for the detection of Cathepsin Z.

Qualité

Evaluated by Western Blotting in human liver tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected Cathepsin Z in 10 µg of human liver tissue lysate.

Description de la cible

~33 kDa observed. (Pungecar, J., et al. (2000). PMID: 10653163)

Forme physique

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Autres remarques

Concentration: Please refer to lot specific datasheet.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable