AB6021

Anti-Stabilin-1 Antibody, CT

from rabbit

• Synonyme(s) : Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1, MS-1 antigen, common lymphatic endothelial and vascular endothelial receptor-1, fasciclin egf-like, laminin-type egf-like, and link domain-containing scavenger re
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: unpurified
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Espèces réactives: human
• Technique(s): immunofluorescence: suitable; immunohistochemistry: suitable (paraffin); western blot: suitable
• Numéro d'accès UniProt: Q9NY15
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... STAB1(23166)

Description

Description générale

Stabilin-1 and Stabilin-2 constitute a novel family of fasciclin domain-containing hyaluronan receptor homologs that may play a role in cell-cell and cell-extracellular matrix interactions in vascular function and inflammatory processes. Stabilin-1 is a transmembrane protein, expressed in endothelial cells within the sinusoidal regions of liver, spleen, and lymph tissues as well as macrophages. Stabilin-2 is absent from the latter (Politz, 2002).

Spécificité

Other notable species homologies include mouse (87%) and rat (83%).

The antibody recognizes the C-terminus of Stabilin-1 within the cytoplasmic region of a cell.

Immunogène

Epitope: C-terminus

GST-tagged recombinant protein corresponding to the C-terminus of human Stabilin-1.

Application

Anti-Stabilin-1 Antibody, C-terminus is an antibody against Stabilin-1 for use in WB, IH(P) & IF.

Immunohistochemistry Analysis: 1:500 dilution from a previous lot detected Stabilin-1 in human placental tertiary villi.
Immunofluorescence Analysis: A previous lot of Anti-Stabilin-1, C-terminus was shown to positively stain using immunofluorescence techniques (Kzhyshkowska, 2008).

Research Category
Cell Structure

Research Sub Category
Adhesion (CAMs)

Qualité

Evaluated by Western blot in HUVEC lysate.
Western blot Analysis: 1:1,000 dilution of this antibody detected Stabilin-1 on 10 µg of HUVEC lysate.

Description de la cible

~ 275 kDa

Forme physique

Format: Unpurified

Unpurified

Unpurified rabbit polyclonal in serum with 0.05% sodium azide.

Stockage et stabilité

Stable for 1 year at -20°C from date of receipt if stored in undiluted aliquots.
Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Remarque sur l'analyse

Control
HUVEC lysate.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1