AB15300

Anti-NECL-1 Antibody

Chemicon^®, from rabbit

• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: mouse
• Fabricant/nom de marque: Chemicon^®
• Technique(s): immunohistochemistry: suitable; western blot: suitable
• Numéro d'accès UniProt: Q8N126
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... CADM3(57863)

Description

Description générale

Nectins are immunoglobulin superfamily adhesion molecules that participate in the organization of epithelial and endothelial junctions. Human and mouse NECL1 share 87.3% identity at the amino acid level (1). NECL1 contains an ectodomain made of three immunoglobulin-like domains, and a cytoplasmic region homologous to those of glycophorin C and contactin-associated protein. NECL1 predominantly expressed in the central nervous system, mainly in neuronal cell bodies in a variety of brain regions including the cerebellum, cerebral cortex and hippocampus. NECL1 localizes to the cell-cell junctions and recruits protein 4.1N to the plasma membranes through its C-terminus, thus may regulate the function of the cell-cell junction.

Spécificité

NECL-1

Immunogène

Synthetic Peptide

Application

Detect NECL-1 using this Anti-NECL-1 Antibody validated for use in IH & WB.

Research Category
Neuroscience

Research Sub Category
Neurofilament & Neuron Metabolism

Western Blot Analysis: NECL-1 can be detected at 1/500 dilution. Testing at further dilution was not conducted.

Immunohistochemistry: 1:50 to 1:1000 straight dilution of Cat. # AB15301 was tested on human medulla oblongata tissue.

Optimal working dilutions must be determined by the end user.

Description de la cible

43 kDa

Forme physique

ImmunoAffinity Purified

Purified Antibody in PBS with 0.1% NaN3

Stockage et stabilité

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.

Remarque sur l'analyse

Control
Tested on Adult mouse brain lysate

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable