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Key Documents

AB10526

Sigma-Aldrich

Anti-COX4 Antibody

from rabbit, purified by affinity chromatography

Synonyme(s) :

cytochrome c oxidase subunit IV isoform 1, cytochrome c oxidase subunit IV1, Cytochrome c oxidase polypeptide IV, cytochrome c oxidase subunit 4 isoform 1, mitochondrial

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Produit purifié par

affinity chromatography

Espèces réactives

human

Conditionnement

antibody small pack of 25 μg

Technique(s)

immunohistochemistry: suitable (paraffin)
western blot: suitable

Numéro d'accès NCBI

NP_001852

Numéro d'accès UniProt

P13073

Conditions d'expédition

ambient

Température de stockage

2-8°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... COX4I1(1327)

Description générale

Cytochrome C oxidase subunit 4 (COX4), is one of 13 subunits of cytochrome c oxidase. Cytochrome c oxidase is responsible for catalyzing the last step of electron transfer through the respiratory chain on the mitochondrial inner membrane. COX4 assembles into sub-complexes with other subunits of cytochrome c oxidase and may represent a rate-limiting intermediate.

Spécificité

Other homologies: Rat and mouse (59% sequence homology).

Immunogène

KLH-conjugated linear peptide corresponding to human COX4.

Application

Anti-COX4 Antibody detects level of COX4 & has been published & validated for use in WB, IH(P).
Immunohistochemistry Analysis: A 1:500 dilution from a previous lot detected COX4 in normal human cardiac muscle tissue.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional

Qualité

Evaluated by Western Blot in human fetal skeletal muscle tissue lysate.

Western Blot Analysis: 0.1 µg/mL of this antibody detected COX4 in 10 µg of human fetal skeletal muscle tissue lysate.

Description de la cible

~17 kDa observed.
A non-specific band may be observed at ~58 kDa

Forme physique

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Remarque sur l'analyse

Control
Human fetal skeletal muscle tissue lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Consulter la Bibliothèque de documents

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Biogerontology, 13(5), 525-536 (2012-09-14)
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Articles

Loading Controls for Western Blotting

Loading controls in western blotting application.

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