8.52016

Fmoc-Phe-OH

Novabiochem^®

• Synonyme(s) : Fmoc-Phe-OH, N-α-Fmoc-L-phenylalanine
• Formule empirique (notation de Hill): C₂₄H₂₁NO₄
• Numéro CAS: 35661-40-6
• Poids moléculaire : 387.43
• Numéro MDL: MFCD00037128
• Code UNSPSC : 12352209
• Numéro de classement CE : 252-661-1
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 400
• Gamme de produits: Novabiochem^®
• Pureté: ≥98% (TLC); ≥98.0% (acidimetric); ≥99.0% (HPLC)
• Forme: powder
• Capacité de réaction: reaction type: Fmoc solid-phase peptide synthesis
• Fabricant/nom de marque: Novabiochem^®
• Pf: 180-188 °C
• Application(s): peptide synthesis
• Groupe fonctionnel: Fmoc
• Température de stockage: 2-30°C
• InChI: 1S/C24H21NO4/c26-23(27)22(14-16-8-2-1-3-9-16)25-24(28)29-15-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h1-13,21-22H,14-15H2,(H,25,28)(H,26,27)
• Clé InChI: SJVFAHZPLIXNDH-UHFFFAOYSA-N

Description

Description générale

High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities.
Standard building block for introduction of phenylalanine amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Fmoc-amino acids for Peptide Production
Cleavage and Deprotection Protocols for Fmoc SPPS

Application

• Drug release from hydrogels: Utilization in the preparation and optimization of amino acid-based double network hydrogels for photocontrolled drug release, showing promise in drug delivery systems (S Xiang et al., 2024).
• Self-assembling biomaterials: Research on self-assembling Fmoc-Phe-OH peptides for the formation of functional biomaterials, applicable in tissue engineering and regenerative medicine (H Ren et al., 2021).

Liaison

Replaces: 04-12-1030

Remarque sur l'analyse

Colour (visual): white to off white
Appearance of substance (visual): powder
Colour index (0,5 M in DMF): ≤ 150 Hazen
Identity (IR): passes test
Enantiomeric purity: ≥ 99.8 % (a/a)
Purity (HPLC): ≥ 99.0 % (a/a)
Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-ß-Ala-Phe-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-Phe-Phe-OH (HPLC): ≤ 0.1 % (a/a)
Assay free amino acid (GC): ≤ 0.2 %
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (25 mmole in 50 ml DMF): clearly soluble
Assay (acidimetric): ≥ 98.0 %
Water (K. F.): ≤ 2.0 %
Ethyl acetate (HS-GC): ≤ 0.5 %
Acetate (IC): ≤ 0.02 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Informations légales

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable