648480

Troponin I, Human Heart

• Synonyme(s) : Troponin I, Human Heart, hcTnI
• Numéro CAS: 77108-40-8
• Numéro MDL: MFCD00213059
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.32

Propriétés

• Pureté: ≥95% (SDS-PAGE)
• Niveau de qualité: 100
• Forme: lyophilized
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze
• Solubilité: urea/Tris buffer (0.02 M Tris, HCl, pH 7.5, 7 M urea, 5 mM EDTA, 15 mM 2-mercaptoethanol): 1 mg/mL
• Conditions d'expédition: ambient
• Température de stockage: −20°C

Description

Description générale

Native troponin I purified from human heart. Inhibitory subunit of troponin that binds to actin in the absence of Ca²⁺, thus inhibiting the ATPase activity of actomyosin. Presence of Tnl in plasma has been used for early detection of myocardial infarction. Useful as a standard in immunoassay and as an immunogen for anti-sera production. Also useful as a tracer for iodination.

Native troponin I purified from human heart. Inhibitory subunit of troponin that binds to actin in the absence of Ca²⁺, thus inhibiting the ATPase activity of actomyosin. Presence of hcTnI in plasma has been used for early detection of myocardial infarction. Useful as a standard in immunoassay and as an immunogen for antisera production. Also useful as a tracer for iodination.

Avertissement

Toxicity: Standard Handling (A)

Forme physique

Lyophilized from 10 mM HCl.

Notes préparatoires

Prepared from tissue of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Autres remarques

Falahati, A., et al. 1999. Am. Heart J. 137, 332.
Mangano, D.T. 1994. Anesthesiology 81, 1317.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany