567051-M

Sinefungin

InSolution, ≥95%, antibiotic

• Synonyme(s) : InSolution Sinefungin, SF, Adenosyl-ornithine, A9145
• Formule empirique (notation de Hill): C₁₅H₂₃N₇O₅
• Numéro CAS: 58944-73-3
• Poids moléculaire : 381.39
• Code UNSPSC : 12352200

Propriétés

• Niveau de qualité: 100
• Essai: ≥95% (HPLC)
• Forme: liquid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; protect from light
• Température de stockage: −20°C
• InChI: 1S/C15H23N7O5/c16-6(1-2-7(17)15(25)26)3-8-10(23)11(24)14(27-8)22-5-21-9-12(18)19-4-20-13(9)22/h4-8,10-11,14,23-24H,1-3,16-17H2,(H,25,26)(H2,18,19,20)/t6-,7-,8+,10+,11+,14+/m0/s1
• Clé InChI: LMXOHSDXUQEUSF-YECHIGJVSA-N

Description

Description générale

An anti-leishmanial nucleoside antibiotic that acts as an S-adenosyl-L-methionine (SAM, AdoMet) methyltransferase-specific inhibitor.

Actions biochimiques/physiologiques

Primary Target
S-adenosyl-L-methionine (SAM, AdoMet) methyltransferase

Avertissement

Toxicity: Standard Handling (A)

Forme physique

A 10 mM (2 mg/524 µl) solution in H₂O.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Autres remarques

Cheng, D., et al. 2004. J. Biol. Chem.279, 23892.
Lin, Q., et al. 2001. J. Am. Chem. Soc.123, 11608.
Zingg, J.M., et al. 1996. Nucleic Acids Res.24, 3267.
McCammon, M.T., and Parks, L.W. 1981. J. Bacteriol.145, 106.
Pugh, C.S.G., et al. 1978. J. Biol. Chem.253, 4075.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3