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411543

Sigma-Aldrich

Mouse Anti-Human IgG₁, Fc Fragment Specific (HP6069) Biotin Conjugate

liquid, clone HP6069, Calbiochem®

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.77

Source biologique

mouse

Niveau de qualité

100

Forme d'anticorps

purified antibody

Type de produit anticorps

secondary antibodies

Clone

HP6069, monoclonal

Forme

liquid

Ne contient pas

preservative

Fabricant/nom de marque

Calbiochem®

Conditions de stockage

OK to freeze
avoid repeated freeze/thaw cycles

Isotype

IgG

Conditions d'expédition

ambient

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Catégories apparentées

Description générale

Purified mouse monoclonal antibody conjugated to biotin. Recognizes human IgG1 Fc fragment.
This Mouse Anti-Human IgG₁, Fc Fragment Specific (HP6069) Biotin Conjugate is validated for use in Enzyme Immunoassay for the detection of Human IgG₁, Fc Fragment Specific.

Application

Enzyme Immunoassay (1:500-1:2000)

Conditionnement

Please refer to vial label for lot-specific concentration.

Avertissement

Toxicity: Standard Handling (A)

Autres remarques

Antibody should be titrated for optimal results in individual systems.



Cross-reactivity by ELISA against human myeloma proteins:

Human IgG1: 100%

Human IgG2: ≤0.1%

Human IgG3: ≤0.2%

Human IgG4: ≤0.1%

Human IgM: ≤0.1%

Human IgA: ≤0.1%

Human IgE: ≤0.1%



Cross-reactivity by ELISA against chimeric antibodies:

Human IgG1: 100%

Human IgG2: <0.02%

Human IgG3: <0.02%

Human IgG4: <0.02%

Human IgM: <0.02%

Human IgA: <0.01%

Human IgE: <0.001%

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

F J Fasullo et al.
Clinical chemistry, 35(3), 364-368 (1989-03-01)
The objective of this study was to develop a clinical laboratory method for subclass typing of human immunoglobulin G (IgG) paraproteins. Serum proteins were isoelectrically focused (IEF) in a mini-gel and passively blotted by capillary diffusion onto untreated nitrocellulose. Unreacted
R G Hamilton
Annales de biologie clinique, 48(7), 473-477 (1990-01-01)
This study demonstrates the utility of a panel of genetically-engineered human-mouse chimeric antibodies with variable region specificity for a hapten, NP, and constant regions analogous to the different human immunoglobulin isotypes as quality control reagents. They performed well as isotype-restricted
R Jefferis et al.
Immunology letters, 10(3-4), 223-252 (1985-01-01)
Seventy-four monoclonal antibodies (McAb) of putative specificity for human IgG (11), the IgG sub-classes (59) or Gm allotypes (4) have been evaluated for reactivity and specificity in eight laboratories employing different assay techniques or protocols. For the IgG, IgG3, IgG4
R G Hamilton
Clinical chemistry, 33(10), 1707-1725 (1987-10-01)
Complement activation, cell surface-receptor binding, blocking activity, and possibly placental transfer are among the biologically important functional differences that have been detected between the four human IgG subclasses by use of polyclonal antisera. In 1985, a IUIS/WHO panel of immunologists

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