1.37148

Triéthanolamine

EMPROVE^® EXPERT, Ph. Eur., JPE, NF

• Synonyme(s) : 2,2′,2′′-nitrilotriéthanol, Tris(2-hydroxyéthyl)amine
• Formule linéaire : (HOCH₂CH₂)₃N
• Numéro CAS: 102-71-6
• Poids moléculaire : 149.19
• Numéro Beilstein : 1699263
• Numéro MDL: MFCD00002855
• Code UNSPSC : 12352104

Propriétés

• Agence: JPE; NF; Ph. Eur.
• Niveau de qualité: 500
• Densité de vapeur: 5.14 (vs air)
• Pression de vapeur: 0.01 mmHg ( 20 °C)
• Gamme de produits: EMPROVE^® EXPERT
• Forme: liquid
• Température d'inflammation spontanée: 600 °F
• Limite d'explosivité: 8.5 %
• Technique(s): API processing | cocrystal formation: suitable
• Indice de réfraction: n20/D 1.485 (lit.)
• Plage de pH utile: 7.3-8.3
• pKa (25 °C): 7.8
• Point d'ébullition: 190-193 °C/5 mmHg (lit.)
• Pf: 17.9-21 °C (lit.)
• Densité: 1.124 g/mL at 25 °C (lit.)
• Application(s): liquid formulation; pharmaceutical; semi-solid formulation
• Température de stockage: 2-25°C
• Chaîne SMILES: OCCN(CCO)CCO
• InChI: 1S/C6H15NO3/c8-4-1-7(2-5-9)3-6-10/h8-10H,1-6H2
• Clé InChI: GSEJCLTVZPLZKY-UHFFFAOYSA-N

Description

Description générale

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Triethanolamine (Trolamine) is a tertiary amine that acts as a basic buffer component, typically used as a final formulation buffer for small molecules pharmaceuticals. It may also be used as a process buffer in cell lysis and biomolecule downstream chromatography.
As a multi-compendial product, Triethanolamine (Trolamine) Emprove^® Expert meets the N-nitrosodiethanolamine limits required by Ph Eur. Also, low microbial and endotoxin limits facilitate the use of this product in high-risk applications.

Informations légales

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 354.2 °F - closed cup
• Point d'éclair (°C): 179 °C - closed cup