1.03893

Acide benzènesulfonique

EMPROVE^® EXPERT

• Synonyme(s) : Benzene sulphonic acid, Benzenesulphonic acid, Besylic acid, Phenylsulfonic acid, Phenylsulphonic acid
• Formule linéaire : C₆H₅SO₃H
• Numéro CAS: 98-11-3
• Poids moléculaire : 158.18
• Numéro Beilstein : 742513
• Numéro CE : 202-638-7
• Numéro MDL: MFCD00011689
• Code UNSPSC : 12352005

Propriétés

• Source biologique: synthetic
• Niveau de qualité: 500
• Gamme de produits: EMPROVE^® EXPERT
• Forme: crystalline
• Technique(s): API processing | cocrystal formation: suitable; API processing | salt formation: suitable
• Impuretés: endotoxins, low
• Application(s): liquid formulation; parenterals; pharmaceutical
• Chaîne SMILES: OS(=O)(=O)c1ccccc1
• InChI: 1S/C6H6O3S/c7-10(8,9)6-4-2-1-3-5-6/h1-5H,(H,7,8,9)
• Clé InChI: SRSXLGNVWSONIS-UHFFFAOYSA-N

Description

Description générale

For protein-based therapeutics, such as monoclonal antibodies (mAbs) or plasma derived proteins, often highly concentrated protein formulations are required to meet intended dosing regimens. However, this usually comes with elevated viscosities and presents a challenge in the manufacturing process and final formulation. Our Viscosity Reduction Excipient Platform reduces the viscosity and helps overcome challenges associated with highly concentrated protein solutions.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation.
Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

The Viscosity Reduction Platform is based on the combination of two new excipients, one amino acid component with one anionic component, that together can better reduce protein viscosity beyond levels achieved with single excipients. Also, combining the two components enables a balance of viscosity reduction and protein stabilization. Benzenesulfonic Acid Emprove^® Expert is part of this new proprietary technology platform.

Conditionnement

1038930500 / 500g / Glass bottle
1038931000 / 1kg / Glass bottle

Informations légales

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS05,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H302,H314
• Conseils de prudence: P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
• Code de la classe de stockage: 8A - Combustible corrosive hazardous materials
• Classe de danger pour l'eau (WGK): WGK 1