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Merck
Toutes les photos(1)

Principaux documents

07-464

Sigma-Aldrich

Anti-Vav3 Antibody, human

Upstate®, from rabbit

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

polyclonal

Espèces réactives

human

Fabricant/nom de marque

Upstate®

Technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotype

IgG

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... VAV3(10451)

Spécificité

Vav3

Immunogène

KLH-conjugated, synthetic peptide corresponding to amino acids 566-591of human Vav3.

Application

Anti-Vav3 Antibody, human detects level of Vav3 & has been published & validated for use in IP, WB, IC, IH.
Research Category
Signaling
Research Sub Category
Cytoskeletal Signaling

Qualité

routinely evaluated by immunoblot in RIPA lysates from HeLa and Jurkat cells

Description de la cible

98 kDa

Forme physique

0.1M Tris-glycine, pH 7.4, 0.15M NaCl,0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein A purified

Stockage et stabilité

2 years at -20°C

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1


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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

VAV proteins as signal integrators for multi-subunit immune-recognition receptors.
Turner, Martin and Billadeau, Daniel D
Nature Reviews: Immunology, 2, 476-486 (2002)
Youjia Cao et al.
The EMBO journal, 21(18), 4809-4819 (2002-09-18)
The Rac/Rho-specific guanine nucleotide exchange factor, Vav-1, is a key component of the T-cell antigen receptor (TCR)-linked signaling machinery. Here we have used somatic cell gene-targeting technology to generate a Vav-1-deficient Jurkat T-cell line. The J.Vav1 cell line exhibits dramatic
Mapping cell-matrix stresses during stretch reveals inelastic reorganization of the cytoskeleton.
Nuria Gavara,Pere Roca-Cusachs,Raimon Sunyer,Ramon Farre,Daniel Navajas
Biophysical Journal null
Emanuela Dylgjeri et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 25(18), 5623-5637 (2019-07-04)
DNA-dependent protein kinase catalytic subunit (DNA-PK) is a pleiotropic kinase involved in DNA repair and transcriptional regulation. DNA-PK is deregulated in selected cancer types and is strongly associated with poor outcome. The underlying mechanisms by which DNA-PK promotes aggressive tumor
Mehdi Badaoui et al.
Cell reports, 32(1), 107842-107842 (2020-07-09)
Pseudomonas aeruginosa (Pa) represents the leading cause of airway infection in cystic fibrosis (CF). Early airways colonization can be explained by enhanced adhesion of Pa to the respiratory epithelium. RNA sequencing (RNA-seq) on fully differentiated primary cultures of airway epithelial

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