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Merck
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Key Documents

05-1567

Sigma-Aldrich

Anti-p120 Catenin Antibody, clone 15D2

clone 15D2, from mouse

Synonyme(s) :

Cadherin-associated Src substrate, catenin (cadherin-associated protein), delta 1, catenin, delta 1, p120 catenin

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

100

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

15D2, monoclonal

Espèces réactives

mouse, human

Réactivité de l'espèce (prédite par homologie)

rat

Technique(s)

flow cytometry: suitable
immunocytochemistry: suitable
western blot: suitable

Isotype

IgG1κ

Numéro d'accès UniProt

O60716

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... CTNND1(1500)

Description générale

p120 Catenin is a cadherin-associated protein that binds intracellular proteins, such as the small GTPase, RhoA, and controls E-cadherin funcation and stability. Proteins of the p120 family and their isoforms are expressed in cells via alternative splicing, and all of them are essential for HGF signaling to Rac1.

Spécificité

Recognizes p120 Catenin

Immunogène

Epitope: C-terminus
Recombinant fusion protein derived from the C-terminus of murine p120

Application

Immunocytochemistry:
Research Category
Signaling
Research Sub Category
Transcription Factors
Use Anti-p120 Catenin Antibody, clone 15D2 (mouse monoclonal antibody) validated in WB, ICC, FC to detect p120 Catenin also known as Cadherin-associated Src substrate ,catenin (cadherin-associated protein) delta 1.

Qualité

Evaluated by Western Blot on Hela cell lysate.
Western Blot Analysis: 1 g/mL of this antibody detected p120 Catenin in lysate from Hela cells.

Description de la cible

90-120 kDa

Liaison

Replaces: 04-237

Forme physique

Format: Purified
Protein G Chromatography
Purified mouse monoclonal in 0.1M Tris-Glycine (pH 7.4), 150mM NaCl and 0.05% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8ºC from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution.

Remarque sur l'analyse

Control
Hela cell lysate.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Joyce Nair-Menon et al.
International journal of molecular sciences, 21(7) (2020-04-11)
The RNA interference (RNAi) machinery is an essential component of the cell, regulating miRNA biogenesis and function. RNAi complexes were thought to localize either in the nucleus, such as the microprocessor, or in the cytoplasm, such as the RNA-induced silencing
Lindy J Pence et al.
International journal of molecular sciences, 22(3) (2021-02-03)
Inflammatory breast cancer is a highly aggressive form of breast cancer that forms clusters of tumor emboli in dermal lymphatics and readily metastasizes. These cancers express high levels of E-cadherin, the major mediator of adherens junctions, which enhances formation of

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