870865P

BMP22

Avanti Polar Lipids, powder

• Synonyme(s) : 4-pentadecylbenzylphosphonic acid
• Formule empirique (notation de Hill): C₂₂H₃₉O₃P
• Numéro CAS: 1306684-90-1
• Poids moléculaire : 382.52
• Code UNSPSC : 12352211

Propriétés

• Pureté: 99% (TLC)
• Forme: powder
• Conditionnement: pkg of 1 × 1 mg (870865P-1mg); pkg of 1 × 5 mg (870865P-5mg)
• Fabricant/nom de marque: Avanti Polar Lipids
• Type de lipide: bioactive lipids
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: CCCCCCCCCCCCCCCC1=CC=C(CP(O)(O)=O)C=C1

Description

Description générale

BMP (bis(monoacylglycerol)phosphate) is synthesized from phosphatidylglycerol (PG) in alveolar macrophages. BMP is a unique phospholipid having a glycerol phosphate ester at sn-1 position rather than sn-3 and has one acyl group attached to each of the glycerol moieties. The acyl groups of BMP is rich in polyunsaturated species.

Actions biochimiques/physiologiques

BMP (bis(monoacylglycerol)phosphate) (BMP) is found in the retinal pigment epithelium of healthy human retina. BMP lipids regulates cholesterol level in endosomes. It is implicated in endosomal/lysosomal storage diseases like Niemann-Pick and neuronal ceroid lipofuscinosis diseases. BMP22/4PBPA is a small molecule inhibitor of autotaxin (ATX). 4PBPA has relatively a longer half-life and also reduces the lysophosphatidic acid concentration in plasma. BMP22 is implicated in reducing the bone erosion and systemic bone loss.

Conditionnement

5ML Glass Amber Screw Cap Vial (870865P-1MG)

5ML Glass Amber Screw Cap Vial (870865P-5MG)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable