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860681P

Avanti

C15 Ceramide-d7 (d18:1-d7/15:0)

Avanti Research™ - A Croda Brand 860681P, powder

Synonyme(s) :

N-pentadecanoyl-D-erythro-sphingosine(d7)

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About This Item

Formule empirique (notation de Hill):
C33H58 D7NO3
Numéro CAS:
67492-15-3
Poids moléculaire :
530.92
Code UNSPSC :
12352100
Nomenclature NACRES :
NA.25

Forme

powder

Conditionnement

pkg of 1 × 1 mg (860681P-1mg)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand 860681P

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

OC[C@]([H])(NC(CCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCC([2H])([2H])C([2H])([2H])C([2H])([2H])[2H]

Description générale

C15 Ceramide (d18:1/15:0) is a synthetic ceramide containing sphingosine with pentadecanoic acid. C15 Ceramide-d7 (d18:1-d7/15:0) is a deuterated derivative of C15 Ceramide (d18:1/15:0).

Application

C15 Ceramide-d7 (d18:1-d7/15:0) has been used as a standard to measure C32–C34 ceramides in zebrafish brain and human embryonic kidney cell line (HEK293) by thermo q-exactive plus quadrupole-orbitrap mass spectrometery. It has also been used to measure the concentration of sphingolipids in right submandibular glands of mice by ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC/MS/MS).

Actions biochimiques/physiologiques

Ceramides serve as precursors for several sphingolipids. Ceramides play a significant role in cell differentiation, proliferation, and apoptosis. In addition, they also acts as secondary transmitters in cell signaling.

Conditionnement

5 mL Amber Glass Screw Cap Vial (860681P-1mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Souvent commandé avec ce produit

Réf. du produit
Description
Tarif

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

No data available

Point d'éclair (°C)

No data available

Certificats d'analyse (COA)

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Claude Vieu et al.
Journal of lipid research, 43(3), 510-522 (2002-03-15)
This study reports a single-step analysis of the molecular species of endogenous ceramides and of the ceramide moiety of sphingomyelins in biological samples, using gas liquid chromatography (GLC). Silylated sphingomyelins were quantitatively converted to monosilylated ceramide upon injection into GLC
Tejia Zhang et al.
Scientific reports, 9(1), 19939-19939 (2019-12-29)
Extensive characterisations of the zebrafish genome and proteome have established a foundation for the use of the zebrafish as a model organism; however, characterisation of the zebrafish lipidome has not been as comprehensive. In an effort to expand current knowledge
Anna Zalewska et al.
Biomolecules, 9(12) (2019-12-19)
This is the first study to investigate the relationship between ceramides, the mitochondrial respiratory system, oxidative stress, inflammation, and apoptosis in the submandibular gland mitochondria of mice with insulin resistance (IR). The experiment was conducted on 20 male C57BL/6 mice
Hady Razak Hady et al.
Journal of clinical medicine, 8(12) (2019-12-18)
The liver plays a central role in the glucose and lipid metabolism. Studies performed on animal models have shown an important role of lipid accumulation in the induction of insulin resistance. We sought to explain whether in obese humans, the

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