850346C

14:1 (Δ9-Cis) PC

1,2-dimyristoleoyl-sn-glycero-3-phosphocholine, chloroform

• Synonyme(s) : 1,2-di-(9Z-tetradecenoyl)-sn-glycero-3-phosphocholine; PC(14:1(9Z)/14:1(9Z))
• Formule empirique (notation de Hill): C₃₆H₆₈NO₈P
• Numéro CAS: 56750-90-4
• Poids moléculaire : 673.90
• Code UNSPSC : 51191904
• Nomenclature NACRES : NA.25

Propriétés

• Pureté: >99% (TLC)
• Forme: liquid
• Conditionnement: pkg of 1 × 2.5 mL (850346C-25mg); pkg of 2 × 4 mL (850346C-200mg)
• Fabricant/nom de marque: Avanti Polar Lipids 850346C
• Concentration: 10 mg/mL (850346C-25mg); 25 mg/mL (850346C-200mg)
• Type de lipide: cardiolipins; phospholipids
• Conditions d'expédition: dry ice
• Température de stockage: −20°C

Description

Description générale

Phosphatidylcholine (PC) belongs to the class of glycerophospholipid. It is the prime cellular phospholipid.

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

14:1 (Δ9-Cis) PC has been used in the liposome preparation. It has also been used as an internal standard for the extraction of lipids from the interstitial fractions of lung tissues for electrospray ionisation-mass spectrometry (ESI-MS) analysis.

Actions biochimiques/physiologiques

Phosphatidylcholine (PC) contributes to the membrane structure. Each cell type and tissue maintain a unique PC profile. PC plays a key role in cell signaling. Disruption in the homeostasis of PC leads to cell death in mammalian cells. PC is present in bile and aids in lipid emulsification in the diet. It is known to reduce cholesterol and triglyceride levels. It is administered for treating fat embolism and cardiac ischemia. Monounsaturated PC 14:1 (Δ9-Cis) is known to inhibit cell proliferation in different cell lines.

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

Conditionnement

5 mL Clear Glass Sealed Ampule (850346C-200mg)

5 mL Clear Glass Sealed Ampule (850346C-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372
• Conseils de prudence: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Classification des risques: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3