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Key Documents

810131P

Avanti

16:0-12:0 NBD PC

Avanti Research - A Croda Brand 810131P, powder

Synonyme(s) :

1-palmitoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphocholine

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About This Item

Formule empirique (notation de Hill):
C42H74N5O11P
Numéro CAS:
Poids moléculaire :
856.04
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

powder

Conditionnement

pkg of 1 × 1 mg (810131P-1mg)
pkg of 5 × 1 mg (810131P-5mg)
pkg of 5 × 2 mg (810131P-10mg)

Fabricant/nom de marque

Avanti Research - A Croda Brand 810131P

Type de lipide

fluorescent lipids
phospholipids

Conditions d'expédition

dry ice

Température de stockage

−20°C

Description générale

Phosphatidylcholine (PC) is the most abundant phospholipid in eukaryotes and a prime metabolite of glycerolipid metabolism. It is present in the mucosal layer of the colon. In NBD PC, the fluorescent 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) label is linked to phosphatidylcholine.

Application

16:0-12:0 NBD PC may be used:
  • in the microfluidic chip-based technology to demonstrate separation of fluorophore-labeled phospholipids and to monitor enzyme activities of lipid-modifying enzymes
  • as a fluorophore for 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) in fluorescence recovery experiments
  • as a substrate to test scramblase activity

Actions biochimiques/physiologiques

The use of 7-nitrobenz-2-oxa-1,3-diazol-4-yl phosphatidylcholine (NBD PC) as fluorescent probes in lipid membranes is involved in the study of various cellular processes.

Conditionnement

5 mL Amber Glass Screw Cap Vial (810131P-10mg)
5 mL Amber Glass Screw Cap Vial (810131P-1mg)
5 mL Amber Glass Screw Cap Vial (810131P-5mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Code de la classe de stockage

11 - Combustible Solids


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

C Scomparin et al.
The European physical journal. E, Soft matter, 28(2), 211-220 (2008-12-23)
The diffusion law of DMPC and DPPC in Supported Lipid Bilayers (SLB), on different substrates, has been investigated in details by Fluorescence Recovery After Patterned Photobleaching (FRAPP). Over micrometer length scales, we demonstrate the validity of a purely Brownian diffusive
Ellen C Wrobel et al.
Physical chemistry chemical physics : PCCP, 22(11), 6154-6166 (2020-03-04)
The antibacterial activity of a calixarene derivative, p-tert-butylcalix[6]arene (Calix6), was assessed and was shown not to inhibit the growth of E. coli, S. aureus and B. subtilis bacteria. With the aim of gaining more insights into the absence of antibacterial
R Derradi et al.
Langmuir : the ACS journal of surfaces and colloids, 35(47), 15232-15241 (2019-11-09)
Matrix vesicles (MVs) are a special class of extracellular vesicles that drive bone and dentin mineralization by providing the essential enzymes and ions for the nucleation and propagation of mineral crystals. Tissue-nonspecific alkaline phosphatase (TNAP) is an integral protein of
Rachel R Kroe et al.
Analytical biochemistry, 390(1), 1-13 (2008-12-24)
Analytical ultracentrifugation is a widely used method for characterizing the solution behavior of macromolecules. However, the two commonly used detectors, absorbance and interference, impose some fundamental restrictions on the concentrations and complexity of the solutions that can be analyzed. The
C Bellefroid et al.
International journal of pharmaceutics, 572, 118793-118793 (2019-11-13)
Dermal administration of different macromolecules, such as nucleic acids, remains a real challenge because of the difficulty of crossing the main skin barrier, the stratum corneum (SC). To overcome this barrier, the use of deformable lipid-based nanovectors were developed to

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